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Displaying results 5281 - 5290 of 7018 in total
  1. Drug

    Trefentanil

    go.drugbank.com/drugs/DB09181
    Experimental

    Trefentanil (A-3665) is a fentanyl analogue opioid developed in 1992. It is more potent and shorter acting than alfentanil. … Trefentanil is not used in clinics due to the severity of its respiratory depression, though it is still used in research.

  2. Drug

    105AD7

    go.drugbank.com/drugs/DB05113
    Investigational

    metastatic colorectal cancer patients. 105AD7 may be a suitable vaccine for treatment of this disease. … 105AD7 is a human monoclonal antibody that mimics the complement regulatory protein, CD55, overexpressed by many solid tumours including osteosarcoma. 105AD7 induced antitumour inflammatory responses in

  3. Drug

    Butropium

    go.drugbank.com/drugs/DB15968
    Experimental

  4. Drug

    MBO7133

    go.drugbank.com/drugs/DB04999
    Experimental

    MB07133 is a HepDirect prodrug of an activated form of cytarabine (araC), an anti-cancer drug that is used to treat leukemia but is ineffective against primary liver cancer. … MB07133 uses our HepDirect technology to target a prodrug form of araCMP specifically to the liver.

  5. Drug

    UB-612

    go.drugbank.com/drugs/DB16444
    Investigational

    The vaccine incorporates a strong S1-RBD component linked to a single chain fragment region (sFC) of a human IgG1, which facilitates cell attachment and acts as the principal neutralizing domain of the … This vaccine was designed to induce a broad immune response. It was able to reduce viral load and prevent COVID-19 infection in a mouse challenge model and in rhesus macaques[L30653, L30658].

  6. Drug

    Actinium Ac 225 Vipivotide tetraxetan

    go.drugbank.com/drugs/DB23637
    Investigational

    Actinium Ac 225 Vipivotide Tetraxetan is a small molecule drug. … Actinium Ac 225 Vipivotide Tetraxetan is under investigation in clinical trial NCT07150715 (Alpha-Emitting Radionuclide or Beta-Emitting Radionuclide With Metastasis-Directed Stereotactic Body Radiotherapy

    Synonyms: Actinium Ac 225 Vipivotide Tetraxetan
  7. Drug

    Phorbol 12-myristate 13-acetate diester

    go.drugbank.com/drugs/DB17045
    Investigational

    Phorbol 12-myristate 13-acetate diester is an inducer of neutrophil extracellular traps (NETs).[A253087]

  8. Drug

    AAV-CNGB3

    go.drugbank.com/drugs/DB18344
    Investigational

    AAV-CNGB3 is an adenovirus associated viral vector serotype 8 containing the human CNGB3 gene.

  9. Drug

    Metelimumab

    go.drugbank.com/drugs/DB18695
    Experimental

    Metelimumab (CAT-192) is a monoclonal antibody targeted against transforming growth factor (TGF) beta-1.

    Synonyms: Immunoglobulin g4, anti-(human transforming growth factor .beta.1 (human monoclonal cat-192 .gamma.4-chain)), disulfide with human monoclonal cat-192 .kappa.-chain, dimer
  10. Drug

    XR5944

    go.drugbank.com/drugs/DB06364
    Experimental

    XR5944 is a DNA bis-intercalating anticancer drug. It has both intercalating and antineoplastic activities.