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Chlormadinone acetate
go.drugbank.com/drugs/DB15903ApprovedWithdrawnIn the US, chlormadinone acetate was formerly marketed as a component of the combination drug products Estalor-21 and C-Quens. … Chlormadinone acetate is a progesterone derivative first synthesized in 1961.
Benzyl benzoate
go.drugbank.com/drugs/DB00676ApprovedScabies is a skin infection caused by the mite sarcoptes scabiei. It is characterised by severe itching (particularly at night), red spots, and may lead to a secondary infection.
Categories: Compounds used in a research, industrial, or household settingButylscopolamine
go.drugbank.com/drugs/DB09300ApprovedInvestigationalVet approvedIt is also effective at preventing bladder spasms. … Butylscopolamine is a peripherally acting antimuscarinic, anticholinergic agent.
Distigmine
go.drugbank.com/drugs/DB13694InvestigationalDistigmine is a parasympathomimetic agent with a longer duration of action and enhanced drug accumulation compared to [DB00545] and [DB01400]. … Distigmine is available in several countries as a treatment of underactive detrusor and voiding dysfunction in the urinary tract where the active ingredient is distigmine bromide.
Nilutamide
go.drugbank.com/drugs/DB00665ApprovedInvestigationalNilutamide is an antineoplastic hormonal agent primarily used in the treatment of prostate cancer. … Nilutamide is a pure, nonsteroidal anti-androgen with affinity for androgen receptors (but not for progestogen, estrogen, or glucocorticoid receptors).
Categories: Androgen Receptor Antagonists, Androgen Receptor InhibitorsAutogene cevumeran
go.drugbank.com/drugs/DB17497InvestigationalAutogene cevumeran is an mRNA-based cancer vaccine targeting an unspecified amount of tumour-associated antigens. It is being investigated for cancers.
SYN-101
go.drugbank.com/drugs/DB05958ExperimentalSYN101 is comprised of an immune cell specific antibody linked to an ALK5 inhibitor payload to selectively block TGF-b signalling in immune cells. … SYN-101 is an investigational antibody-drug conjugate developed for the treatment of cancer.
Edotreotide gallium Ga-68
go.drugbank.com/drugs/DB15494ApprovedEdotreotide gallium Ga-68 is an 8 amino acid peptide bound to the chelator 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA). … [L8597] [Dotatate gallium Ga-68] is used for a similar indication.[A185852] Dotatate gallium Ga-68 has lower tumor uptake but this data is highly variable between patients.
Caficrestat
go.drugbank.com/drugs/DB15121InvestigationalAT-001 is under investigation in clinical trial NCT03062384 (AT-001 for Long-term Preservation of Brain Health in Aging).