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Elasomeran
go.drugbank.com/drugs/DB15654ApprovedInvestigationalacute respiratory syndrome coronavirus 2 (SARS-CoV-2). … The Moderna COVID-19 Vaccine (mRNA-1273; Elasomeran) is a novel mRNA-based vaccine encapsulated in a lipid nanoparticle that encodes for a full-length pre-fusion stabilized spike (S) protein of severe
Synonyms: MRNA-1273 SARS-COV-2Mixtures: Spikevax Bivalent (original / Omicron Ba.4/5)Ad5-nCoV
go.drugbank.com/drugs/DB15655InvestigationalAd5-nCoV is a recombinant adenovirus type-5 vector (Ad5) vaccine currently being investigated for prophylaxis against SARS-CoV-2. … The study will evaluate antibody response in healthy patients between the ages of 18 and 60 who will receive one of three study doses, with follow-up taking place at weeks 2 and 4 and months 3 and 6 post-vaccination
Synonyms: Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector)Ala-geninthiocin
go.drugbank.com/drugs/DB15657ExperimentalAla-geninthiocin is a novel thiopeptide antibacterial compound derived from marine _Streptomyces_ species.
N4-Hydroxycytidine
go.drugbank.com/drugs/DB15660ExperimentalN4-Hydroxyctidine, or EIDD-1931, is a ribonucleoside analog which induces mutations in RNA virions. … [A193008,A193011] N4-hydroxycytidine was first described in the literature in 1980 as a potent mutagen of bacteria and phage.
Synonyms: beta-D-N-4-Hydroxycytidine, 4-N-HydroxycytidineCategories: Heterocyclic Compounds, 1-RingMolnupiravir
go.drugbank.com/drugs/DB15661Investigational[A193014] A [remdesivir] resistant mutant mouse hepatitis virus has also been shown to have increased sensitivity to N4-hydroxycytidine. … [A193029] Recent studies have shown molnupiravir inhibits replication of human and bat coronaviruses, including SARS-CoV-2, in mice and human airway epithelial cells.
Categories: Heterocyclic Compounds, 1-RingProducts: LAGEVRIO® 200MG CAPSULASSisunatovir
go.drugbank.com/drugs/DB15674InvestigationalSisunatovir is under investigation in clinical trial NCT04267822 (Study of RV521 in the Treatment of Adult Subjects Who Have Undergone HCT With an URTI With RSV).
Categories: Heterocyclic Compounds, 2-RingBaloxavir
go.drugbank.com/drugs/DB15675InvestigationalBaloxavir is under investigation in clinical trial NCT04327791 (Combination Therapy With Baloxavir and Oseltamavir 1 for Hospitalized Patients With Influenza (The COMBO Trial 1)).
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 3-RingNeisseria meningitidis group W-135 capsular polysaccharide tetanus toxoid conjugate antigen
go.drugbank.com/drugs/DB15683ApprovedInvestigationalSynonyms: Neisseria meningitidis group W-135 capsular polysaccharide tetanus toxoid conjugate antigen, Nimenrix component neisseria meningitidis group W-135 capsular polysaccharide tetanus toxoid conjugate antigenTridecactide
go.drugbank.com/drugs/DB15687InvestigationalTridecactide, also known as alpha-corticotropin 1-13, is a deacetylated and deaminated alpha-melanocyte stimulating hormone, which may have antipyretic, anti-inflammatory, and antimicrobial effects.
Synonyms: alpha-1-13-corticotropin, human