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Displaying results 5331 - 5340 of 10000 in total
  1. Pathway

    Cardiolipin Biosynthesis CL(22:5(7Z,10Z,13Z,16Z,19Z)/16:1(9Z)/16:0/16:0)

    smpdb.ca/view/SMP0236937
    Metabolic

    PA is then transferred to the inner mitochondrial membrane to continue cardiolipin synthesis. … Second, the mitochondrial outer membrane enzyme glycerol-3-phosphate acyltransferase esterifies an acyl-group to the sn-1 position of sn-glycerol 3-phosphate to form 1-acyl-sn-glycerol 3-phosphate (lysophosphatidic

    Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphate
  2. Drug

    Eldelumab

    go.drugbank.com/drugs/DB06116
    Investigational

    MDX-1100, a fully human antibody that targets IP10 (also known as CXCL10), a chemokine expressed in association with multiple inflammatory disease indications, such as rheumatoid arthritis, inflammatory

  3. Drug

    Fosphenytoin

    go.drugbank.com/drugs/DB01320
    ApprovedInvestigational

    Its main mechanism is to block frequency-dependent, use-dependent and voltage-dependent neuronal sodium channels, and therefore limit repetitive firing of action potentials. … It works by slowing down impulses in the brain that cause seizures.

    Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Substrates
  4. Pathway

    Phosphatidylcholine Biosynthesis PC(16:0/22:5(4Z,7Z,10Z,13Z,16Z))

    smpdb.ca/view/SMP0014327
    Metabolic

    to phosphatidylcholine. … Second, choline-phosphate cytidylyltransferase, localized to the endoplasmic reticulum membrane, catalyzes the conversion of phosphocholine to CDP-choline.

    Drugs: Ademetionine · Choline · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium +2 more
  5. Pathway

    Phosphatidylcholine Biosynthesis PC(16:0/22:5(7Z,10Z,13Z,16Z,19Z))

    smpdb.ca/view/SMP0014328
    Metabolic

    to phosphatidylcholine. … Second, choline-phosphate cytidylyltransferase, localized to the endoplasmic reticulum membrane, catalyzes the conversion of phosphocholine to CDP-choline.

    Drugs: Ademetionine · Choline · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium +2 more
  6. Pathway

    Phosphatidylcholine Biosynthesis PC(16:1(9Z)/22:4(7Z,10Z,13Z,16Z))

    smpdb.ca/view/SMP0014355
    Metabolic

    to phosphatidylcholine. … Second, choline-phosphate cytidylyltransferase, localized to the endoplasmic reticulum membrane, catalyzes the conversion of phosphocholine to CDP-choline.

    Drugs: Ademetionine · Choline · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium +2 more
  7. Pathway

    Phosphatidylcholine Biosynthesis PC(22:5(4Z,7Z,10Z,13Z,16Z)/16:0)

    smpdb.ca/view/SMP0014914
    Metabolic

    to phosphatidylcholine. … Second, choline-phosphate cytidylyltransferase, localized to the endoplasmic reticulum membrane, catalyzes the conversion of phosphocholine to CDP-choline.

    Drugs: Ademetionine · Choline · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium +2 more
  8. Pathway

    Phosphatidylethanolamine Biosynthesis PE(16:1(9Z)/22:4(7Z,10Z,13Z,16Z))

    smpdb.ca/view/SMP0015194
    Metabolic

    Second, choline-phosphate cytidylyltransferase, localized to the endoplasmic reticulum membrane, catalyzes the conversion of phosphocholine to CDP-choline. … They are the second most abundant phospholipid in eukaryotic cell membranes, and contrary to phosphatidylcholine, it is concentrated with phosphatidylserine in the cell membrane's inner leaflet.

    Drugs: Choline · Serine · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · Ethanolamine +1 more
  9. Pathway

    Phosphatidylethanolamine Biosynthesis PE(22:4(7Z,10Z,13Z,16Z)/16:1(9Z))

    smpdb.ca/view/SMP0015726
    Metabolic

    Second, choline-phosphate cytidylyltransferase, localized to the endoplasmic reticulum membrane, catalyzes the conversion of phosphocholine to CDP-choline. … They are the second most abundant phospholipid in eukaryotic cell membranes, and contrary to phosphatidylcholine, it is concentrated with phosphatidylserine in the cell membrane's inner leaflet.

    Drugs: Choline · Serine · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · Ethanolamine +1 more
  10. Pathway

    Phosphatidylethanolamine Biosynthesis PE(22:5(4Z,7Z,10Z,13Z,16Z)/16:0)

    smpdb.ca/view/SMP0015754
    Metabolic

    Second, choline-phosphate cytidylyltransferase, localized to the endoplasmic reticulum membrane, catalyzes the conversion of phosphocholine to CDP-choline. … They are the second most abundant phospholipid in eukaryotic cell membranes, and contrary to phosphatidylcholine, it is concentrated with phosphatidylserine in the cell membrane's inner leaflet.

    Drugs: Choline · Serine · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · Ethanolamine +1 more