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Displaying results 5341 - 5350 of 10000 in total
  1. Drug

    Fludrocortisone

    go.drugbank.com/drugs/DB00687
    ApprovedInvestigational

    [A187169,A187187] It is functionally similar to [aldosterone], the body's primary endogenous mineralocorticoid, and is structurally analogous to [cortisol], differing only by a fluorine atom at the 9-position … Fludrocortisone is a synthetic mineralocorticoid used in conjunction with [hydrocortisone] to replace missing endogenous corticosteroids in patients with adrenal insufficiency.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: FLOCURTIN® 0.1 MG TABLETAS, ASTONIN-H 0,1 MG TABLET, 100 ADET
  2. Drug

    Manganese gluconate

    go.drugbank.com/drugs/DB11141
    Approved

    Manganese gluconate is a direct ingredient in food substances as a nutrient supplement. In pharmaceutical preparations it is used as a [DB06757] supplement. … It is typically obtained by reacting manganese carbonate with gluconic acid in aqueous medium and then crystallizing the product to form a slightly pink powder.

    Mixtures: Vitamin E 400 Iu With Selenium, Vitamin C & Manganese, Cal-mag Plus K, Mn and Zn CapletsSynonyms: Manganese D-gluconate
  3. Drug

    Pazopanib

    go.drugbank.com/drugs/DB06589
    ApprovedInvestigational

    Pazopanib is a small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity. It is developed by GlaxoSmithKline and was FDA approved on October 19, 2009.

    Categories: MATE 1 Inhibitors, Heterocyclic Compounds, 1-RingProducts: VOTRIENT® 200 MG, VOTRIENT® 400 MG
  4. Drug

    Roxadustat

    go.drugbank.com/drugs/DB04847
    ApprovedInvestigational

    It works by reducing the breakdown of the hypoxia-inducible factor (HIF), which is a transcription factor that stimulates red blood cell production in response to low oxygen levels. … Roxadustat is a first-in-class hypoxia-inducible factor prolyl hydroxylase inhibitor used to treat anemia associated with chronic kidney disease.

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingProducts: Ernevod 50 mg Film Kaplı Tablet (12 adet), EVRENZO 50 MG FİLM KAPLI TABLET, 12 ADET
  5. Drug

    Selenium

    go.drugbank.com/drugs/DB11135
    ApprovedInvestigationalVet approved

    Selenium is a trace metal in the human body particularly important as a component of glutathione peroxidase, an important enzyme in the prevention of cellular damage by free radicals and reactive oxygen

    International brands: B-Traxim SeMixtures: Coen.q10w.vit.c and E Beta-car.se Cu Zn Mn, Vitamin E 400 Iu and Selenium 25 Mcg Capsules
  6. Drug

    Sulodexide

    go.drugbank.com/drugs/DB06271
    ApprovedInvestigationalWithdrawn

    Sulodexide is a mixture of glycosaminoglycans (GAGs) composed of dermatan sulfate (DS) and fast moving heparin (FMH).

    Products: ANJIOFLUX 600 LRU 2 ML ENJEKTABL COZELTI ICEREN 10 AMPUL, VESSEL DUE F
  7. Drug

    Intermedine

    go.drugbank.com/drugs/DB17612
    Investigational

    Synonyms: N-acetyl-acth(1-13)-amide, Valinamide, acetyl-l-seryl-l-tyrosyl-l-seryl-l-methionyl-l-glutamyl-l-histidyl-l-phenylalanyl-l-arginyl-l-tryptophyl-glycyl-l-lysyl-l-prolyl-, l-Categories: Heterocyclic Compounds, 2-Ring
  8. Drug

    Aluminum sulfate

    go.drugbank.com/drugs/DB11239
    Approved

    Medically, it is primarily used as a coagulating agent in minor cuts and abrasions as well as deodorant [L2144]. … Aluminum (Al) is ubiquitous and represents the third most common element in the Earth’s crust. It most commonly exists in a combined state with various other elements.

    Mixtures: DALIDOMEPOLVO SACHET 2.2 G, DOMEBORO® POLVOProducts: Gingi-Aid MAX Z-Twist 1, Stingose Asp 373mg/ml
  9. Drug

    Moexipril

    go.drugbank.com/drugs/DB00691
    ApprovedInvestigational

    Moexipril is a non-sulfhydryl containing precursor of the active angiotensin-converting enzyme (ACE) inhibitor moexiprilat. It is used to treat high blood pressure (hypertension). … It works by relaxing blood vessels, causing them to widen. Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems.

    Mixtures: UNIRETIC 15 MG/ 25 MG FILM KAPLI TABLET, 30 ADET, UNIRETIC 7,5 MG/ 12.5 MG FILM KAPLI TABLET, 30 ADETCategories: Heterocyclic Compounds, 2-Ring, Agents Acting on the Renin-Angiotensin System
  10. Drug

    Dabrafenib

    go.drugbank.com/drugs/DB08912
    ApprovedInvestigational

    Dabrafenib mesylate (Tafinlar) is a reversible ATP-competitive kinase inhibitor and targets the MAPK pathway. … It was approved on May 29, 2013, for the treatment of melanoma with V600E or V6000K mutation.[L41955] It was also used for metastatic non-small cell lung cancer with the same mutation.

    Categories: Heterocyclic Compounds, 1-Ring, Organic Anion Transporter 1 InhibitorsProducts: TAFINLAR® 50 MG CÁPSULAS DURAS, TAFINLAR®75 MG CÁPSULAS DURAS