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Brentuximab
go.drugbank.com/drugs/DB05471Investigationalto on normal cells. … SGN-30 has been shown to induce direct anti-cancer activity towards tumor cells expressing CD30 and is undergoing phase II trials for cancer therapy.
Antipain
go.drugbank.com/drugs/DB15251Experimental[A214490] The binding of antipain to OPB has been used in molecular dynamic studies to identify other OPB inhibitors with more favourable pharmacodynamic and pharmacokinetic properties for potential development … [A214481] Early studies investigated the potential for antipain to alter DNA damage and chromosomal aberrations in irradiated cells or those treated with chemical mutagens such as _N_-methyl-_N_'-nitro
Covax-19™
go.drugbank.com/drugs/DB15846InvestigationalCovax-19™ was tested in animal studies, and shown to achieve potent antibody and T-cell responses against the COVID-19 spike protein. … As of June 2020, the vaccine is in Phase 1 trials to evaluate safety and immune responses (NCT04428073).
AVR-RD-01
go.drugbank.com/drugs/DB17651InvestigationalAVR-RD-01 is an investigational _ex vivo_ lentiviral gene therapy developed by AVROBIO Inc.
Ginsenoside Rg1
go.drugbank.com/drugs/DB06750ExperimentalNutraceuticalBecause ginsenosides appear to affect multiple pathways, their effects are complex and difficult to isolate. Rg1 Appears to be most abundant in Panax ginseng (Chinese/Korean Ginseng).
Azosemide
go.drugbank.com/drugs/DB08961InvestigationalAzosemide is a loop diuretic used to treat hypertension, edema, and ascites.
FT516
go.drugbank.com/drugs/DB15732InvestigationalThis compound expresses a high-affinity 158V, CD16 (hnCD16) Fc receptor that has an enhanced binding ability to tumor-targeting antibodies, and is resistant to downregulation.
Carbomycin
go.drugbank.com/drugs/DB11383ExperimentalVet approvedThe structure of carbomycin was generated in 1957 by Robert Woodward and later modified in 1965.
ABX1100
go.drugbank.com/drugs/DB17655InvestigationalIt was first developed by Aro Biotherapeutics and is being investigated for the treatment of Pompe disease.[L45978]