Search
Periciazine
go.drugbank.com/drugs/DB01608ApprovedPericiazine is a phenothiazine of the piperidine group. … It is used as an adjunctive medication in some psychotic patients, for the control of residual prevailing hostility, impulsiveness and aggressiveness.
Synonyms: 2-Cyano-10-(3-(4-hydroxypiperidino)propyl)phenothiazine, 2-Cyano-10-(3-(4-hydroxy-1-piperidyl)propyl)phenothiazineCOVID-19 Nucleocapsid-GM-CSF Protein Lactated Ringer's Injection
go.drugbank.com/drugs/DB15845ExperimentalThe vaccine utilizes granulocyte macrophage-colony stimulating factor (GM-CSF), a cytokine known to enhance vaccine efficacy through prolongation of humoral and cell immunity. … As of July 2020, Medicine Invention Design, Inc. is sponsoring a small, controlled clinical trial for the COVID-19 AP TP Vaccine for ‘proof of concept.’
Synonyms: AP-TP-V, COVID-19 AP TP VaccineTiagabine
go.drugbank.com/drugs/DB00906ApprovedTiagabine is an anti-convulsive medication. It is also used in the treatment for panic disorder as are a few other anticonvulsants. … Though the exact mechanism by which tiagabine exerts its effect on the human body is unknown, it does appear to operate as a selective GABA reuptake inhibitor.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesObstructive Sleep Apnea (OSA)
go.drugbank.com/conditions/DBCOND0040865Drugs: ModafinilSynonyms: Obstructive Sleep Apnea (SAOS)Gepotidacin
go.drugbank.com/drugs/DB12134ApprovedInvestigational[A273755] By inhibiting two distinct bacterial enzymes, a lower potential for the development of resistance to gepotidacin is expected. … Gepotidacin is a first-in-class triazaacenaphthylene antibacterial targeting bacterial DNA gyrase and topoisomerase IV.[L52685] Its target is similar to that of fluoroquinolone antibacterials - e.g.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesDesoxycorticosterone pivalate
go.drugbank.com/drugs/DB01134ExperimentalVet approvedDesoxycorticosterone pivalate is a mineralocorticoid hormone and an analog of desoxycorticosterone. It is white, odorless, and stable in air. … Federal (U.S.A.) law restricts this drug to use by or on the order of a licensed veterinarian.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesInternational brands: Cortexone M, Percorten MTrichlormethiazide
go.drugbank.com/drugs/DB01021ApprovedVet approvedA thiazide diuretic with properties similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p830)
International brands: Diu-HydrinElagolix
go.drugbank.com/drugs/DB11979ApprovedInvestigationalAs of 24 July 2018, however, the U.S. … Moreover, women who are affected by this condition can suffer for up to six to ten years and visit multiple physicians before receiving a proper diagnosis [A35868, A35869, F801].
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersRelmapirazin
go.drugbank.com/drugs/DB19130InvestigationalRelmapirazin is under investigation in clinical trial NCT05425719 (Pharmacokinetics and Safety of MB-102 (Relmapirazin) and the Medibeacon Transdermal GFR Measurement System in Evaluation of Kidney Function
Synonyms: D-serine, n,n'-((3,6-diamino-2,5-pyrazinediyl)dicarbonyl)bis-, N,n'-((3,6-diamino-2,5-pyrazinediyl)dicarbonyl)bis(d-serine)Cardiolipin Biosynthesis CL(16:1(9Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/18:4(6Z,9Z,12Z,15Z)/18:4(6Z,9Z,12Z,15Z))
smpdb.ca/view/SMP0211740MetabolicCardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...