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Pazopanib
go.drugbank.com/drugs/DB06589ApprovedInvestigationalPazopanib is a small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity. It is developed by GlaxoSmithKline and was FDA approved on October 19, 2009.
Categories: MATE 1 Inhibitors, Heterocyclic Compounds, 1-RingProducts: VOTRIENT® 200 MG, VOTRIENT® 400 MGRoxadustat
go.drugbank.com/drugs/DB04847ApprovedInvestigationalIt works by reducing the breakdown of the hypoxia-inducible factor (HIF), which is a transcription factor that stimulates red blood cell production in response to low oxygen levels. … Roxadustat is a first-in-class hypoxia-inducible factor prolyl hydroxylase inhibitor used to treat anemia associated with chronic kidney disease.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingProducts: Ernevod 50 mg Film Kaplı Tablet (12 adet), EVRENZO 50 MG FİLM KAPLI TABLET, 12 ADETCoagulation Factor IX (Recombinant)
go.drugbank.com/drugs/DB00100ApprovedIt has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, and has structural and functional characteristics similar to those of endogenous factor IX. … medium that is then processed and purified for use as a pharmaceutical agent.
Products: BENEFIX 250 IU IV ENJEKSIYONLUK COZELTI ICIN TOZ VE COZUCU, 1 ADET, BENEFIX 500 IU IV ENJEKSIYONLUK COZELTI ICIN TOZ VE COZUCU, 1 ADETKraurosis Vulvae
go.drugbank.com/conditions/DBCOND0114418Synonyms: Lichen sclerosus et atrophicus, Lichen sclerosus et atropicusChlorambucil
go.drugbank.com/drugs/DB00291ApprovedInvestigationalAlthough it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed) … A nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases.
Synonyms: N,N-di-2-chloroethyl-γ-p-aminophenylbutyric acid, N,N-di-2-chloroethyl-gamma-p-aminophenylbutyric acidProducts: LEUKERAN 2 MG TABLET, 25 ADET, Leukeran 2 mg - FilmtablettenOxazepam
go.drugbank.com/drugs/DB00842ApprovedOxazepam is an intermediate-acting, 3-hydroxybenzodiazepine used in the treatment of alcohol withdrawal and anxiety disorders. … Oxazepam, like related 3-hydroxybenzodiazepine [lorazepam], is considered less susceptible to pharmacokinetic variability based on patient-specific factors (e.g. age, liver disease) - this feature is advantageous
Categories: Heterocyclic Compounds, 2-RingProducts: Praxiten 15 mg - Tabletten, Praxiten 50 mg - TablettenDanazol
go.drugbank.com/drugs/DB01406ApprovedInvestigationalA synthetic steroid with antigonadotropic and anti-estrogenic activities that acts as an anterior pituitary suppressant by inhibiting the pituitary output of gonadotropins. … It possesses some androgenic properties. Danazol has been used in the treatment of endometriosis and some benign breast disorders.
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsProducts: CIPLADANOGEN® 200 MG CAPSULAS, DANASIN 50 MG KAPSUL, 100 ADETEplerenone
go.drugbank.com/drugs/DB00700ApprovedInvestigationalThe resulting increased plasma renin activity and aldosterone circulating levels do not overcome the effects of eplerenone. … regulatory feedback of aldosterone on renin secretion.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: EPLERENON HEU 50 MG NET, EPLERENON HEU 25 MG NETShea butter
go.drugbank.com/drugs/DB14311ApprovedShea butter is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Products: EM Shea Butter CreamTenapanor
go.drugbank.com/drugs/DB11761ApprovedInvestigationala novel alternative in the treatment of IBS-C. … Tenapanor is a novel, small molecule medication approved in September 2019 for the treatment of constipation-predominant irritable bowel-syndrome (IBS-C).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: XPHOZAH 10 mg, XPHOZAH 20 mg