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ABBV-514
go.drugbank.com/drugs/DB17586InvestigationalABBV-514 is in development for the treatment of non-small cell lung cancer (NSCLC) and head and neck squamous cell carcinoma (HNSCC) as a single agent and in combination with a PD-1 inhibitor.[L45464]
Metisazone
go.drugbank.com/drugs/DB13641ExperimentalCategories: Antivirals for Systemic Use, Antiinfectives for Systemic UseTalampicillin
go.drugbank.com/drugs/DB13814ExperimentalCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseAnethole
go.drugbank.com/drugs/DB15916ApprovedWithdrawnCategories: Compounds used in a research, industrial, or household settingXL228
go.drugbank.com/drugs/DB05184InvestigationalXL228 is a novel anticancer compound designed to inhibit the insulin-like growth factor type-1 receptor (IGF1R), Src and Abl tyrosine kinases – targets that play crucial roles in cancer cell proliferation
Vociprotafib
go.drugbank.com/drugs/DB21559InvestigationalVociprotafib has a monoisotopic molecular weight of 450.16 Da. … Vociprotafib is under investigation in clinical trial NCT05054725 (Combination Study of RMC-4630 and Sotorasib for NSCLC Subjects With KRASG12C Mutation After Failure of Prior Standard Therapies).
Carrimycin
go.drugbank.com/drugs/DB16476InvestigationalCategories: Experimental Unapproved Treatments for COVID-19Col-118
go.drugbank.com/drugs/DB05778InvestigationalCOL-118, a topical compound based on the SansRosa technology, for the treatment of redness associated with rosacea and other skin disorders. … Col-118 is a unique formulation and presentation of Brimonidine, which is a selective alpha-2 adrenergic receptor agonist.
Halofuginone
go.drugbank.com/drugs/DB04866InvestigationalVet approvedHalofuginone is a low molecular weight quinazolinone alkaloid, and a potent inhibitor of collagen alpha1(I) and matrix metalloproteinase 2 (MMP-2) gene expression. … Collgard Biopharmaceuticals is developing halofuginone for the treatment of scleroderma and received orphan drug designation from the U.S. Food and Drug Administration in March, 2000.