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Zuclopenthixol
go.drugbank.com/drugs/DB01624ApprovedInvestigationalIt is known that zuclopenthixol is metabolized by Cytochrome P450 2D6. Zuclopenthixol was approved for use in Canada in 2011, but is not approved for use in the United States. … These are organic polycyclic compounds containing a thioxanthene moiety, which is an aromatic tricycle derived from xanthene by replacing the oxygen atom with a sulfur atom.
Ribavirin
go.drugbank.com/drugs/DB00811ApprovedInvestigationalIt is primarily indicated for use in treating hepatitis C and viral hemorrhagic fevers. … The potential use of ribavirin as a treatment for acute myeloid leukemia is currently under investigation.
Mixtures: Rebetron Ready To Use Solution (albumin(human)free) (6000000 Iu/ml and 200mg Capsules)Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseIndium In-111 pentetate
go.drugbank.com/drugs/DB09425ApprovedIndium In-111 pentetate disodium is a radioactive diagnostic indicated for use in radionuclide cisternography. … Decay of In-111 by electron capture allows for detection with a gamma camera for visualization of the brain and spinal column.
Diazoxide
go.drugbank.com/drugs/DB01119ApprovedInvestigational[A190372] When administered intravenously, diazoxide can be used to treat hypertensive emergencies;[L44622] however, this specific form of diazoxide is no longer available in the US. … [A255647,L44612] It is chemically related to thiazide diuretics but does not inhibit carbonic anhydrase and does not have chloriuretic or natriuretic activity.
Tozinameran
go.drugbank.com/drugs/DB15696ApprovedInvestigational[A225386,L15007] Comirnaty is undergoing evaluation in clinical trials in both the USA (NCT04368728) and Germany (NCT04380701). … Comirnaty is also approved for use as a fourth booster shot in adults 50 years of age and older.[L41350]
Eugenol
go.drugbank.com/drugs/DB09086ApprovedInvestigationalThere are a number of unapproved OTC products available containing eugenol that advertise its use for the treatment of toothache. … Eugenol is a naturally occurring phenolic molecule found in several plants such as cinnamon, clove, and bay leaves.
Mixtures: Test Thin-Layer Rapid Use Patch TestBictegravir
go.drugbank.com/drugs/DB11799ApprovedInvestigationalBictegravir is a recently approved investigational drug that has been used in trials studying the treatment of HIV-1 and HIV-2 infection. It has been approved for HIV-1 monotherapy combined with 2 other antiretrovirals in a single tablet.
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseRemdesivir
go.drugbank.com/drugs/DB14761ApprovedInvestigational[L12174, L12177] After initially being granted an FDA Emergency Use Authorization (EUA) on May 1st, 2020,[L13236] remdesivir was fully approved by the FDA for the treatment of COVID-19 on October 22 … [L39640] Remdesivir in combination with [baricitinib] for the treatment of COVID-19, was granted an FDA Emergency Use Authorization on November 19, 2020.[L22619]
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UsePlazomicin
go.drugbank.com/drugs/DB12615ApprovedOn June 28th, 2018, plazomicin sulfate was approved by the FDA for use in adult patients for the treatment of complicated urinary tract infections (cUTI) including Pyelonephritis. … Developed by Achaogen biopharmaceuticals, plazomicin is a next-generation aminoglycoside synthetically derived from [DB12604].
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseStrontium chloride
go.drugbank.com/drugs/DB13987ApprovedWithdrawnSrCl2 is useful in reducing tooth sensitivity by forming a barrier over microscopic tubules in the dentin containing nerve endings that have become exposed by gum recession [A33167, A33168]. … This kind of barrier protection for tooth hypersensitivity has, however, been superseded by other toothpaste formulations and ingredients designed to be nerve calming agents instead [A33167, A33168].