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Displaying results 5411 - 5420 of 10000 in total
  1. Drug

    Cinitapride

    go.drugbank.com/drugs/DB08810
    Investigational

    It is marketed in Spain and Mexico.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeSynonyms: 4-Amino-N-(1-(3-cyclohexen-1-ylmethyl)-4-piperidyl)-2-ethoxy-5-nitrobenzamide
  2. Drug

    Vicasinabin

    go.drugbank.com/drugs/DB21587
    Investigational

    Vicasinabin has a monoisotopic molecular weight of 358.2 Da. … Vicasinabin is under investigation in clinical trial NCT04265261 (A Study to Investigate the Efficacy and Safety of RG7774 in Patients With Diabetes Mellitus Type 1 or Type 2 With Treatment-Naive Diabetic

  3. Drug

    Faldaprevir

    go.drugbank.com/drugs/DB11808
    Investigational

    Faldaprevir has been investigated for the treatment of Chronic Hepatitis C.

    Categories: Antivirals for treatment of HCV infections
  4. Drug

    R411

    go.drugbank.com/drugs/DB05468
    Experimental

    It is a dual-acting competitive integrin antagonist (as compared to previously developed single integrin antagonists or SIAs) that prevents binding of V-CAM1 to either a4b1 or a4b7. … R411 is a non-steroid oral medicine for the treatment of asthma. It is not immunosuppressive, but blocks the activation and recruitment of cells involved in respiratory inflammation.

  5. Drug

    Ifenprodil

    go.drugbank.com/drugs/DB08954
    ApprovedInvestigationalWithdrawn

    Binding at the LBD of the agonists glycine (or D-serine) to the GluN1 subunits and of glutamate to the GluN2 subunits is a regulatory mechanism for channel activation. … [A220118, A220128] NMDARs are heterotetramers that typically involve a dimer of dimers of both GluN1 and GluN2A-D subunits, with each subunit itself composed of an N-terminal domain (NTD), a ligand-binding

  6. Drug

    Tizaterkib

    go.drugbank.com/drugs/DB21296
    Investigational

    Tizaterkib has a monoisotopic molecular weight of 494.2 Da. … Tizaterkib is under investigation in clinical trial NCT04305249 (Safety and Preliminary Efficacy of ATG-017 Monotherapy or Combination Therapy With Nivolumab in Advanced Solid Tumors and Hematological

  7. Drug

    Stanolone

    go.drugbank.com/drugs/DB02901
    IllicitInvestigational

    A potent androgenic metabolite of testosterone. Dihydrotestosterone (DHT) is generated by a 5-alpha reduction of testosterone.

    Synonyms: 17beta-Hydroxyandrostan-3-one, 17β-hydroxy-5α-androstan-3-oneCategories: Sex Hormones and Modulators of the Genital System
  8. Drug

    Redaporfin

    go.drugbank.com/drugs/DB17219
    Investigational

    Synonyms: 3,3',3'',3'''-(7,8,17,18-tetrahydroporphyrin-5,10,15,20-tetrayl)tetrakis(2,4-difluoro-n-methylbenzenesulfonamide), Benzenesulfonamide, 3,3',3'',3'''-(7,8,17,18-tetrahydro-21h,23h-porphine-5,10,15,20-tetrayl)tetrakis(2,4-difluoro-n-methyl-Categories: Heterocyclic Compounds with 4 or More Rings
  9. Drug

    iCo-007

    go.drugbank.com/drugs/DB05268
    Investigational

    iCo-007 (formerly known as ISIS 13650) is a second generation antisense compound being developed by iCo for the treatment of various eye diseases caused by the formation of new blood vessels (angiogenesis … ) such as age-related macular degeneration (AMD) and diabetic retinopathy(DR).

  10. Drug

    Amrubicin

    go.drugbank.com/drugs/DB06263
    Investigational

    In 2002, Amrubicin was approved and launched for sale in Japan based on Phase 2 efficacy data in both SCLC and NSCLC. … of Amrubicin [L1714, L1716].