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ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2
go.drugbank.com/bio_entities/BE0001241TargetHumansCatalyzes both the synthesis of cyclic ADP-beta-D-ribose (cADPR) from NAD(+), and its hydrolysis to ADP-D-ribose (ADPR) (PubMed:7805847). Cyclic ADPR is known to serve as an endogenous second messenger that elicits calcium release from i...
Synonyms: Bone marrow stromal cell antigen 1Veliflapon
go.drugbank.com/drugs/DB16346InvestigationalVeliflapon is under investigation in clinical trial NCT00353067 (Veliflapon (Dg-031)to Prevent Heart Attacks or Stroke in Patients With a History of Heart Attack or Unstable Angina).
Categories: Analgesics, Non-Narcotic, Anti-Inflammatory Agents, Non-SteroidalDengue virus serotype 4
go.drugbank.com/drugs/DB22667Approved[L53368] Qdenga was approved for use in the European Union in December 2022.[L53373]
Epirizole
go.drugbank.com/drugs/DB08991ExperimentalEpirizole is an oral nonsteroidal anti-inflammatory drug (NSAID) used for muscle and joint pain.
Categories: Analgesics, Non-Narcotic, Non COX-2 selective NSAIDSLevorphanol
go.drugbank.com/drugs/DB00854ApprovedA narcotic analgesic that may be habit-forming. It is nearly as effective orally as by injection.
Sonlicromanol
go.drugbank.com/drugs/DB16333InvestigationalSonlicromanol is under investigation in clinical trial NCT04165239 (The KHENERGYZE Study).
Categories: Vitamin E, analogs & derivatives, Compounds used in a research, industrial, or household settingSynonyms: (S)-6-Hydroxy-2,5,7,8-Tetramethyl-N-((R)-Piperidin-3-Yl)Chroman-2-CarboxamideSeliciclib
go.drugbank.com/drugs/DB06195InvestigationalDeveloped by Cyclacel, seliciclib is being researched for the treatment of non-small cell lung cancer (NSCLC), leukemia, HIV infection, herpes simplex infection, and the mechanisms of chronic inflammation
OAV201
go.drugbank.com/drugs/DB17842ExperimentalIt was first developed by Novartis and investigated for the treatment of Rett syndrome, but further investigation in clinical trials was halted.[L46661] … OAV201 is a non-replicating, recombinant adeno-associated virus serotype 9 (AAV9) containing the human Methyl CpG Binding Protein 2B (MECP2B) cDNA under the control of a segment of the murine MECP2 promoter
Indirubin
go.drugbank.com/drugs/DB12379InvestigationalIndirubin is under investigation in clinical trial NCT01735864 (Dosage Determination Trial for Indigo Naturalis Extract in Oil Ointment).
Categories: Compounds used in a research, industrial, or household settingPhenoxybenzamine
go.drugbank.com/drugs/DB00925ApprovedInvestigationalAn alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.