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Carafiban
go.drugbank.com/drugs/DB19813ExperimentalCarafiban has a monoisotopic molecular weight of 465.2 Da. … Carafiban is a small molecule drug. The usage of the INN stem '-fiban' in the name indicates that Carafiban is a fibrinogen receptor antagonist (glycoprotein IIb/IIIa receptor antagonist).
Licostinel
go.drugbank.com/drugs/DB19864ExperimentalLicostinel has a monoisotopic molecular weight of 274.95 Da. … Licostinel is a small molecule drug. The usage of the INN stem '-stinel' in the name indicates that Licostinel is a N-methyl-D-aspartate (NMDA) receptor co-agonist.
Orbofiban
go.drugbank.com/drugs/DB20676ExperimentalOrbofiban has a monoisotopic molecular weight of 361.18 Da. … Orbofiban is a small molecule drug. The usage of the INN stem '-fiban' in the name indicates that Orbofiban is a fibrinogen receptor antagonist (glycoprotein IIb/IIIa receptor antagonist).
Gantofiban
go.drugbank.com/drugs/DB20951ExperimentalGantofiban has a monoisotopic molecular weight of 447.21 Da. … Gantofiban is a small molecule drug. The usage of the INN stem '-fiban' in the name indicates that Gantofiban is a fibrinogen receptor antagonist (glycoprotein IIb/IIIa receptor antagonist).
Roxifiban
go.drugbank.com/drugs/DB21089ExperimentalRoxifiban has a monoisotopic molecular weight of 447.21 Da. … Roxifiban is a small molecule drug. The usage of the INN stem '-fiban' in the name indicates that Roxifiban is a fibrinogen receptor antagonist (glycoprotein IIb/IIIa receptor antagonist).
Sibrafiban
go.drugbank.com/drugs/DB21420ExperimentalSibrafiban has a monoisotopic molecular weight of 420.2 Da. … Sibrafiban is a small molecule drug. The usage of the INN stem '-fiban' in the name indicates that Sibrafiban is a fibrinogen receptor antagonist (glycoprotein IIb/IIIa receptor antagonist).
Padoprazan
go.drugbank.com/drugs/DB21689ExperimentalPadoprazan has a monoisotopic molecular weight of 405.12 Da. … Padoprazan is a small molecule drug. The usage of the INN stem '-prazan' in the name indicates that Padoprazan is a proton pump inhibitor, not dependent on acid activation.
Zerencotrep
go.drugbank.com/drugs/DB21710ExperimentalZerencotrep has a monoisotopic molecular weight of 524.11 Da. … Zerencotrep is a small molecule drug. The usage of the INN stem '-cotrep' in the name indicates that Zerencotrep is a transient receptor potential canonical channel 5 (TRPC5) antagonist.
Plazomicin
go.drugbank.com/drugs/DB12615ApprovedThe structure of plazomicin was established via appending hydroxylaminobutyric acid to [DB12604] at position 1 and 2-hydroxyethyl group at position 6' [A33942]. … It is marketed as Zemdri and is administered via once-daily intravenous infusion.
Categories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexThyroid, porcine
go.drugbank.com/drugs/DB09100ApprovedInvestigational[A190831] Thyroid extract is no longer considered a first line therapy as it delivers a dose that is inconsistent with the stated strength of the tablet. … [A190831,L11755] Thyroid extract has been described in literature to treat hypothyroidism since 1891[A190807] but its use dates back as far as the 6th century.