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Forkhead box protein M1
go.drugbank.com/bio_entities/BE0014280TargetHumansTranscription factor regulating the expression of cell cycle genes essential for DNA replication and mitosis (PubMed:19160488, PubMed:20360045).
Synonyms: HNF-3/fork-head homolog 11Rupintrivir
go.drugbank.com/drugs/DB05102ExperimentalRupintrivir is a rhinovirus 3C protease inhibitor in development for use against human rhinoviral (HRV) infections.
2-(5-fluoro-pentyl)-2-methyl-malonic-acid
go.drugbank.com/drugs/DB16029Investigational2-(5-fluoro-pentyl)-2-methyl-malonic-acid is under investigation in clinical trial NCT00696943 (18F ML-10 for Early Detection of Response of Brain Metastases to SRS).
Fonadelpar
go.drugbank.com/drugs/DB16169InvestigationalFonadelpar is under investigation in clinical trial NCT03527212 (A Study to Assess the Safety and Effectiveness of SJP-0035 for the Treatment of Patients With Dry Eye Disease).
MaxAdFVIII
go.drugbank.com/drugs/DB17713ExperimentalFirst developed by GenStar, it is being investigated for the treatment of hemophilia.
APR-2020
go.drugbank.com/drugs/DB18497InvestigationalAPR-2020 is a CD34+ cells that have been transduced in vitro with a lentiviral vector carrying a codon-optimized sequence for expressing the wild type RPS19 protein
Visugromab
go.drugbank.com/drugs/DB18894InvestigationalVisugromab is under investigation in clinical trial NCT06059547 (Neoadjuvant Immunotherapy in Combination With the Anti-gdf-15 Antibody Visugromab (CTL-002) for Treatment of Muscle Invasive Bladder Cancer
177Lu-PSMA-I&T
go.drugbank.com/drugs/DB22176Investigational177Lu-PSMA-I&T is under investigation in clinical trial NCT04886986 (Phase I/II 225Ac-J591 Plus 177Lu-PSMA-I&T for Progressive Metastatic Castration Resistant Prostate Cancer).
Befunolol
go.drugbank.com/drugs/DB09013ExperimentalIt is currently in experimental status, and is being tested for the management of open angle glaucoma.
OSI-7836
go.drugbank.com/drugs/DB05837ExperimentalIt is also more active than ara-C (another clinically used nucleoside analog) in all nine models and more active than either paclitaxel or cisplatin in the two lung xenograft models tested.