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Cocarboxylase
go.drugbank.com/drugs/DB01987ApprovedInvestigationalThe coenzyme form of Vitamin B1 present in many animal tissues. It is a required intermediate in the pyruvate dehydrogenase complex and the ketoglutarate dehydrogenase complex.
Floctafenine
go.drugbank.com/drugs/DB08976ApprovedWithdrawnFloctafenine is an anti-inflammatory analgesic similar in action to aspirin. Floctafenine inhibits prostaglandin synthesis.
Rexin G
go.drugbank.com/drugs/DB16450InvestigationalRexin-G is a tumor-targeted, injectable retroviral vector carrying a mutant form of the cyclin G1 gene. … It is under development by Epeius Biotechnologies for the potential treatment of metastatic cancer. It is also being investigated for preventing SARSCOV-2 viral entry.
Synonyms: DeltaRex-G Retroviral Vector Encoding a Cyclin G1 InhibitorCarmofur
go.drugbank.com/drugs/DB09010ApprovedWithdrawnCarmofur is a derivative of fluorouracil, and is an antineoplastic agent that has been used in the treatment of breast and colorectal cancer. Carmofur has been known to induce leukoencephalopathy.
MC-1
go.drugbank.com/drugs/DB05315ExperimentalMedicure's MC-1 drug is a cardio-protectant, designed to reduce the damage to the heart when arteries are blocked and when they are subsequently reopened after bypass surgery.
Lemzoparlimab
go.drugbank.com/drugs/DB17572InvestigationalLemzoparlimab is under investigation in clinical trial NCT04912063 (Study to Evaluate Adverse Events and Movement of Lemzoparlimab in Body When Used Intravenously (IV) With Azacitidine Subcutaneously or … IV and Venetoclax Orally in Participants With Acute Myeloid Leukemia and With Azacitidine With or Without Venetoclax in Participants With Myelodysplastic Syndrome).
PGX-100
go.drugbank.com/drugs/DB06114InvestigationalIt is a nearly nonanticoagulant heparin derivative that retains its anti-inflammatory activity. … PGX-100 is an intravenous dosage form of modified heparin.
RG2417
go.drugbank.com/drugs/DB05055InvestigationalRG2417 is a proprietary formulation of uridine, a biological compound essential for the synthesis of DNA and RNA, the basic hereditary material found in all cells, and numerous other factors essential … The rationale for uridine therapy in neuropsychiatric disorders is supported by preclinical and clinical research.
Reproterol
go.drugbank.com/drugs/DB12846InvestigationalReproterol has been used in trials studying the treatment of Asthma, Exercise-Induced.