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Temocapril
go.drugbank.com/drugs/DB08836InvestigationalTemocapril is a prodrug-type angiotensin-I converting enzyme (ACE) inhibitor not approved for use in the United States, but is approved in Japan and South Korea.
Azaperone
go.drugbank.com/drugs/DB11376InvestigationalVet approvedMore rarely it may be used in humans as an antipsychotic drug, but this is uncommon. … It is subsequently employed predominantly as a veterinary tranquilizer and mainly for pigs and elephants.
Categories: Hypnotics and SedativesProducts: AZANIL 40MG/ML INJECTIONTopsalysin
go.drugbank.com/drugs/DB05160InvestigationalTopsalysin is being developed for the treatment of localized prostate cancer and also benign prostatic hyperplasia. Topsalysin is delivered locally to the prostate under ultrasound guidance.
Categories: Amino Acids, Peptides, and ProteinsVoacamine
go.drugbank.com/drugs/DB04877ExperimentalVoacamine is an alkaloid isolated from the bark of the _Pescheria fuchsiae folia_ tree. It is an antimalarial drug approved for use in several African countries.
GTI-2501
go.drugbank.com/drugs/DB05406ExperimentalGTI-2501 is a novel antisense drug which has shown a favorable safety profile in preclinical studies, and in a phase I clinical trial. … Initial testing has demonstrated strong antitumor activity in preclinical studies in prostate cancer and a variety of other tumor types.
Categories: Nucleic Acids, Nucleotides, and NucleosidesMycobacterium w. Vaccine
go.drugbank.com/drugs/DB15798InvestigationalThe Mycobacterium w (M.w) vaccine is a heat-killed suspension derived from a non-pathogenic mycobacterium: mycobacterium indicus pranii. … M.w immunization activates macrophages and lymphocytes upon administration. It has protective efficacy against M. tuberculosis and M. leprae.
Proparacaine
go.drugbank.com/drugs/DB00807ApprovedVet approvedProparacaine is a topical anesthetic drug of the amino ester group. It is found in ophthalmic solutions at a concentration of 0.5% as the hydrochloride salt.
International brands: Ak-TaineMixtures: Fluorescein Sodium and Proparacaine HydrochlorideIndoramin
go.drugbank.com/drugs/DB08950ApprovedWithdrawnIndoramin is a discontinued piperidine antiadrenergic drug with the trade names Baratol and Doralese. … It is a selective alpha-1 adrenergic antagonist with no reflex tachycardia and direct myocardial depression action.
Categories: Benzamides and benzamide derivativesSC12267
go.drugbank.com/drugs/DB05125InvestigationalSC12267 is a novel, small molecule agent from the class of DMARDs (disease modifying anti-rheumatic drug) for the therapy of autoimmune diseases such as rheumatoid arthritis or multiple sclerosis.
Cyclopentamine
go.drugbank.com/drugs/DB08999ApprovedWithdrawnCyclopentamine was an over the counter treatment for nasal congestion in Europe and Australia. … It has been widely discontinued due to the safety, effectiveness, and availability of a similar drug, propylhexedrine.