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Ertugliflozin
go.drugbank.com/drugs/DB11827ApprovedInvestigational[A31581] Ertugliflozin was first approved by the FDA in December 2017.[A261951, L1132] It was also approved by the European Commission in March 2018.[L48621] … Ertugliflozin is a sodium-dependent glucose cotransporter-2 (SGLT2) inhibitor used to treat type II diabetes mellitus. It works to block glucose reabsorption from the glomerulus.
Mixtures: Steglujan (Ertugliflozin 5mg/Sitagliptin 100mg) Film-Coated Tablets, Segluromet (Ertugliflozin 2.5mg/ Metformin 500mg) Film-Coated TabletCategories: Drugs Used in Diabetes, Alimentary Tract and MetabolismThiothixene
go.drugbank.com/drugs/DB01623ApprovedA thioxanthine used as an antipsychotic agent. Its effects are similar to the phenothiazine antipsychotics.
Products: Navane Cap 2mg, Navane Capsules 10mgBendamustine
go.drugbank.com/drugs/DB06769ApprovedInvestigationalThrough this function as an alkylating agent, bendamustine causes intra- and inter-strand crosslinks between DNA bases resulting in cell death. … Bendamustine is a nitrogen mustard drug which has been used in the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL).
Categories: Antineoplastic and Immunomodulating AgentsProducts: BENDAMUS 25MG IV INFÜZYON IÇIN LIYOFILIZE TOZ IÇEREN FLAKON, FLAKON, 1 ADET, XEBINA®100MGPolyethylene glycol
go.drugbank.com/drugs/DB09287ApprovedInvestigationalVet approvedPolyethylene glycol (PEG) is a synthetic polymer produced via polymerization of ethylene oxide molecules to make joining units of ethylene glycol by an ether linkage. … [A190975,A190978] PEGs are water-soluble polymers that can form hydrogen bonds in a ratio of 100 water molecules per one PEG molecule.
Mixtures: Salinol Sol 160mg, MUVITON® CON ELECTROLITOSCategories: Alimentary Tract and Metabolism, Compounds used in a research, industrial, or household settingOxytocin
go.drugbank.com/drugs/DB00107ApprovedInvestigationalVet approved[A229008] It plays an important role in pair bonding, social cognition and functioning, and even fear conditioning. … [A229108] Oxytocin continues to be an important tool in modern obstetrics to induce labor when indicated and to manage postpartum hemorrhage.
Categories: Pituitary and Hypothalamic Hormones and Analogues, Oxytocin and AnaloguesProducts: OXITOCINA 10 UI, OXITOCINA INYECCION 10 UINitroprusside
go.drugbank.com/drugs/DB00325ApprovedInvestigationalNitroprusside serves as a source of nitric oxide, a potent peripheral vasodilator that affects both arterioles and venules (venules more than arterioles). … Nitroprusside is often administered intravenously to patients who are experiencing a hypertensive emergency.
Categories: Nitrates and Nitrites, Indicators and ReagentsProducts: NITROPRUSIATO DE SODIO USP 25MG/ML, DBL SODIUM NITROPRUSSIDE INJECTION 50mg/2mlLixisenatide
go.drugbank.com/drugs/DB09265ApprovedInvestigationalIt is sold by Sanofi-Aventis under the brand name Adlyxin in the US[L763] and Lyxumia in the EU.[L764] Adlyxin recieved FDA approval July 28, 2016.[L763] … Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist used in the treatment of type II diabetes mellitus (T2DM).
Mixtures: LYXUMIA SOLUTION FOR INJECTION IN PRE-FILLED PEN 10MCG AND 20MCG (50mcg/mL and 100mcg/mL), LYXUMIA SOLUTION FOR INJECTION IN PRE-FILLED PEN 10MCG AND 20MCG (50mcg/mL and 100mcg/mL)Categories: Drugs Used in Diabetes, Alimentary Tract and MetabolismTetanus immune globulin, human
go.drugbank.com/drugs/DB11604ApprovedInvestigationalTetanus Immune Globulin is manufactured from human plasma [FDA Label]. It contains antibodies against tetanus toxoid and is primarily used as prophylaxis against tetanus in wounded patients.
Categories: Amino Acids, Peptides, and Proteins, Immune Sera and ImmunoglobulinsProducts: TETANUS GAMMA KEDRION ® 250 UI/1 ML, IG TETANOAtracurium besylate
go.drugbank.com/drugs/DB00732ApprovedIts lack of significant cardiovascular effects and its lack of dependence on good kidney function for elimination provide clinical advantage over alternate non-depolarizing neuromuscular blocking agents
Products: ATRACURIUM LABATEC IV SOLUTION FOR INJECTION 10MG/ML, TRACRIUM INJECTION 25MG/2.5MLFlecainide
go.drugbank.com/drugs/DB01195ApprovedInvestigationalWithdrawn[A186880] Flecainide’s development began in 1966 and was first synthesized in 1972 as an attempt to generate new anesthetics. … [A186931] It is used to prevent supraventricular and ventricular arrhythmias, as well as paroxysmal atrial fibrillation and flutter.
Categories: Antiarrhythmics, Class I, Antiarrhythmics, Class IcSynonyms: N-(2-Piperidinylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide