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Displaying results 541 - 550 of 10000 in total
  1. Drug

    Diethylpropion

    go.drugbank.com/drugs/DB00937
    ApprovedIllicitInvestigational

    A appetite depressant considered to produce less central nervous system disturbance than most drugs in this therapeutic category.

    Synonyms: 1-phenyl-2-diethylamino-1-propanone, 2-(diethylamino)-1-phenyl-1-propanoneProducts: Nobesine 75 Sustained Release Capsule 75mg
  2. Drug

    Vinflunine

    go.drugbank.com/drugs/DB11641
    ApprovedInvestigational

    Efficacy and safety of vinflunine has not been studied in patients with performance status of 2 or less. … Like other vinca agents, vinflunine is an anti-mitotic agent that induces a cell cycle arrest at the G2/M phase and promotes cell death via apoptosis [L1396].

    Categories: Heterocyclic Compounds, 2-Ring, P-glycoprotein substrates with a Narrow Therapeutic IndexSynonyms: 4'-deoxy-20',20'-difluoro-5'-norvincaleukoblastine, 20',20'-difluoro-3',4'-dihydrovinorelbine
  3. Drug

    Cenobamate

    go.drugbank.com/drugs/DB06119
    ApprovedInvestigational

    [L10653] Cenobamate was granted FDA approval on 21 November 2019.[L10653] … [A188442,L10653] The exact mechanism of action has not been described in the literature, though it positively modulates GABA<sub>A</sub> and inhibits voltage gated sodium channels.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersProducts: XCOPRI TITRATION PACK 12.5 mg, 25 mg, XCOPRI TITRATION PACK 50 mg, 100 mg
  4. Drug

    Montelukast

    go.drugbank.com/drugs/DB00471
    ApprovedInvestigational

    worldwide via millions of prescriptions annually and has since become available as a generic and as a brand name product. … Montelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair.

    Synonyms: (R-(E))-1-(((1-(3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropaneacetic acid, 1-[[[(1 R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl] phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]sulfanyl]methyl]cyclopropaneacetic acidMixtures: BROCRIPTIN® 10 MG/ 5 MG, LEPIXOS 5 MG/10 MG FILM TABLET ,30 ADET
  5. Drug

    Gadodiamide

    go.drugbank.com/drugs/DB00225
    ApprovedInvestigational

    Gadodiamide is a linear, non-ionic gadolinium-based contrast agent (GBCA) that is used in magnetic resonance imaging (MRI) procedures to assist in the visualization of blood vessels. … [A263086,A263091] GBCAs constitute the largest group of MR agents, and they are thought to be safer than nonionic iodinated contrast agents.

    Categories: Compounds used in a research, industrial, or household settingProducts: SCANIX 287 MG/ML IV ENJEKSİYONİÇİN ÇÖZELTİ İÇEREN FLAKON, 15 ML, GADOTU 287 MG/ML IV ENJEKSIYON IÇIN ÇÖZELTI IÇEREN FLAKON,15 ML
  6. Drug

    Mecobalamin

    go.drugbank.com/drugs/DB03614
    ApprovedInvestigational

    Mixtures: Levomefolate Calcium Pyridoxal-5 Phosphate Mecobalamin Algal, Levomefolate Calcium, Pyridoxal 5-phosphate, Methylcobalamin and Schizochytrium DHA OilCategories: Vitamin B Complex, Heterocyclic Compounds, 1-Ring
  7. Drug

    Colistimethate

    go.drugbank.com/drugs/DB01111
    ApprovedInvestigationalVet approved

    Colistimethate is an antibiotic that has been shown to have bactericidal activity against aerobic gram-negative microorganisms.

    Products: COLINTENSIN 2M UI, COLIJECT ® 150 MG / VIAL
  8. Drug

    Iopromide

    go.drugbank.com/drugs/DB09156
    Approved

    favorable safety profile, with only 0.7% of patients in a 2 years study experiencing adverse events. … It functions as a contrast agent by opacifying blood vessels in the flow path of the contrast agent, permitting radiographic visualization of the internal structures until significant hemodilution occurs

    Synonyms: N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(methoxyacetyl)amino]-N-methylisophthalamideCategories: Compounds used in a research, industrial, or household setting, X-Ray Contrast Activity
  9. Drug

    Donepezil

    go.drugbank.com/drugs/DB00843
    ApprovedInvestigational

    In 2016, the global burden of dementia was estimated to be 43.8 million, demonstrating a significant increase from a global prevalence of 20.2 million in 1990. … [A182411] Donepezil, also known as Aricept, is a piperidine derivative acetylcholinesterase inhibitor used in the management of the dementia of Alzheimer's Disease, and in some cases, is used to manage

    Mixtures: DEMENT COMBİ 10 MG / 5 MG AĞIZDA DAĞILAN TABLET, 7 TABLET, EBICOMB 5 MG/5 MG EFERVESAN TABLET, 28 ADETCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-Ring
  10. Drug

    Eftrenonacog alfa

    go.drugbank.com/drugs/DB11608
    Approved

    When untreated, most patients die from bleeding complications before 25 years of age [A31557]. … Eftrenonacog alfa is a long-acting recombinant fusion protein used in the treatment of hemophilia B.

    Products: ALPROLIX® 250 UI