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Midostaurin
go.drugbank.com/drugs/DB06595ApprovedInvestigationalMidostaurin (as Rydapt) is a multitarget kinase inhibitor for the treatment for adult patients with newly diagnosed acute myeloid leukemia (AML) who have a specific genetic mutation called FLT3. … It was approved on April 28, 2017 and has shown to increase the overall survival rate in patients with AML as an adjunct therapy along with chemotherapeutic agents.
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexGuanethidine
go.drugbank.com/drugs/DB01170ApprovedWithdrawnIt is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues. … An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves.
Resorcinol
go.drugbank.com/drugs/DB11085ApprovedInvestigationalIt is used as an antiseptic and disinfectant in topical pharmaceutical products in the treatment of skin disorders and infections such as acne, seborrheic dermatitis, eczema, psoriasis, corns, calluses … Although it is primarily indicated for use as a topical application, resorcinol also possesses a well-documented anti-thyroidal activity that is generally not relied upon for any kind of formal therapeutic
Mixtures: Well at Walgreens Anti-Itch Maximum Strength, Well at Walgreens Anti-Itch Maximum StrengthSynonyms: m-Hydroquinone, m-hydroxyphenolAllantoin
go.drugbank.com/drugs/DB11100ApprovedInvestigationalAllantoin is a substance that is endogenous to the human body and also found as a normal component of human diets [FDA Label]. … More specifically, allantoin is a diureide of glyoxylic acid that is produced from uric acid. It is a major metabolic intermediate in most organisms.
Mixtures: Le Stick A Levres Onybel, Essential Solution Vita A Mask SheetProducts: ATOMU Essence A, AC Control SerumWitch hazel
go.drugbank.com/drugs/DB11111ApprovedInvestigationalNutraceuticalMixtures: Hemorrhoidal Soothing Well at WalgreensProducts: A Breath of Fresh Air, Ac Clear Treatment MaskMineral oil
go.drugbank.com/drugs/DB11057ApprovedInvestigationalVet approvedMineral oil, or paraffin oil, is a mixture of higher alkanes from a mineral source, such as petroleum. … It is also used as a mild laxative for human or veterinary uses.
Mixtures: AGAROL CON SABOR A FRAMBUESA, Lubricant PMProducts: Gelee Laxative A LA FramboiseMinoxidil
go.drugbank.com/drugs/DB00350ApprovedInvestigationalA potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.
Products: MINOXIDIL CREMA AL 2%, RENOBELL LOCION AL 5%Rivaroxaban
go.drugbank.com/drugs/DB06228ApprovedInvestigationalRivaroxaban is an anticoagulant and the first orally active direct factor Xa inhibitor. Unlike warfarin, routine lab monitoring of INR is not necessary. … However there is no antidote available in the event of a major bleed. Only the 10 mg tablet can be taken without regard to food. The 15 mg and 20 mg tablet should be taken with food.
Products: Ag-rivaroxaban, M-rivaroxabanBrompheniramine
go.drugbank.com/drugs/DB00835ApprovedHistamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria.
Mixtures: AP-Hist DM, Altidec AMeradimate
go.drugbank.com/drugs/DB11096ApprovedMeradimate, before known as menthyl anthranilate, is used in a maximal concentration of 5% in different products as a UV filter. … [T200] It is currently required to be named as meradimate in all FDA approved OTC products. Meradimate is approved by the FDA and Health Canada to be used as an ingredient in sunblocking products.
Mixtures: CeraVe AM BROAD SPECTRUM SUNSCREEN SPF 30, CeraVe AM Facial Moisturizing Broad Spectrum SPF 30 Sunscreen