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Displaying results 5511 - 5520 of 10000 in total
  1. Drug

    Caldaret

    go.drugbank.com/drugs/DB06231
    Investigational

  2. Drug

    Carboxin

    go.drugbank.com/drugs/DB04657
    ApprovedWithdrawn

    A systemic agricultural fungicide and seed treatment agent.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: 5,6-Dihydro-2-methyl-N-phenyl-1,4-oxathiin-3-carboxamide
  3. Indication

    Breast Adenocarcinoma

    go.drugbank.com/conditions/DBCOND0029215
    Drugs: Thiotepa
    Synonyms: Ca breast, Ca breast - NOS
  4. Drug

    Cycrimine

    go.drugbank.com/drugs/DB00942
    Approved

    Cycrimine is a drug used to reduce levels of acetylcholine to return a balance with dopamine in the treatment and management of Parkinson's disease.

  5. Drug

    mRNA-3705

    go.drugbank.com/drugs/DB17668
    Investigational

    mRNA-3705 is an investigational mRNA encoding methylmalonic CoA mutase (MUT) enzyme. Developed by Moderna TX Inc., it is being investigated for the treatment of methylmalonic academia.[A258843]

  6. Drug

    Virginiamycin M1

    go.drugbank.com/drugs/DB01669
    Experimental

    Pristinamycin IIA is a macrolide antibiotic, a member of the streptogramin A group of antibiotics, and one component of pristinamycin. It is produced by Streptomyces graminofaciens and other bacteria.

    Categories: Amino Acids, Peptides, and Proteins
  7. Target

    Calcium/calmodulin-dependent protein kinase kinase 1

    go.drugbank.com/bio_entities/BE0009418
    TargetHumans

    Calcium/calmodulin-dependent protein kinase that belongs to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Phosphorylates CAMK1, CAMK1D, CAMK1G and CAMK4. … Involved in regulating cell apoptosis. Promotes cell survival by phosphorylating AKT1/PKB that inhibits pro-apoptotic BAD/Bcl2-antagonist of cell death

    Synonyms: CaM-KK 1, CaM-KK alpha
  8. Drug

    Pirlindole

    go.drugbank.com/drugs/DB09244
    Experimental

    The antidepressant efficacy and safety of pirlindole have been demonstrated in numerous studies and, supported by many years of clinical experience in the treatment of depression. … This drug is classified as a reversible inhibitor of monoamine oxidase A enzyme (also known as a RIMA drug). It was developed and is currently used as an antidepressant in Russia.

    Synonyms: 2,3,3a,4,5,6-Hexahydro-8-methyl-1H-pyrazino(3,2,1-jk)carbazole
  9. Drug

    Brodalumab

    go.drugbank.com/drugs/DB11776
    ApprovedInvestigational

    Brodalumab has been used in trials studying the treatment of Asthma, Psoriasis, Crohn's Disease, Psoriatic Arthritis, and Rheumatoid Arthritis. … Brodalumab was FDA approved in February, 2017 as Siliq for the treatment of moderate-to-severe plaque psoriasis.

    Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating Agents
  10. Drug

    BB 21217

    go.drugbank.com/drugs/DB17373
    Investigational

    BB 21217 is an anti-BCMA CAR T cell therapy that uses the same CAR molecule as [idecabtagene vicleucel] (bb2121), but adds the PI3K inhibitor bb007 during ex vivo culture to enrich the drug product (DP