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Displaying results 5531 - 5540 of 10000 in total
  1. Drug

    INM005

    go.drugbank.com/drugs/DB16499
    Investigational

    INM005 was under investigation in clinical trials for the treatment of COVID-19. It was studied for pharmacokinetics, efficacy, and safety in a completed trial (NCT04494984). … Additionally, a retrospective cohort study investigated the effectiveness and safety of specific hyperimmune equine serum for severe hospitalized COVID-19 patients (NCT04954235)

    Synonyms: INM-005 (PURIFIED FAB'2 FRACTION OF EQUINE HYPERIMMUNE SERUM GENERATED FROM ANTIGENIC STIMULATION WITH THE SARS-COV2 RBD PROTEIN)
  2. Drug

    Muparfostat

    go.drugbank.com/drugs/DB05808
    Investigational

    Muparfostat (PI-88) is a mixture of highly sulfated, monophosphorylated mannose oligosaccharides, derived from the extracellular phosphomannan of the yeast Pichia (Hansenula) holstii, with potential antiangiogenic

    Synonyms: -D-MANNAN, (1->3)-, 6-(DIHYDROGEN PHOSPHATE) TRIS(HYDROGEN SULFATE)
  3. Drug

    Methaqualone

    go.drugbank.com/drugs/DB04833
    ApprovedIllicitWithdrawn

    Methaqualone is a sedative-hypnotic drug that is similar in effect to barbiturates, a general central nervous system depressant. … It has also been used illegally as a recreational drug, commonly known as Quaaludes, Sopors, Ludes or Mandrax (particularly in the 1970s in North America) depending on the manufacturer.

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-Ring
  4. Drug

    Iratumumab

    go.drugbank.com/drugs/DB05550
    Investigational

    Molecular weight is approximately 170,000 daltons. In phase I/II clinical trials for treatment of CD30+ lymphomas.

  5. Drug

    Oxantel

    go.drugbank.com/drugs/DB13670
    Investigational

    Oxantel is an anthelmintic drug that targets parasitic acetylcholine receptors.[A275093, A275098]

    Mixtures: PAMOATO DE OXANTEL 250 MG/5ML + PAMOATO DE PIRANTEL 250 MG/5 ML SUSPENSIÓN., VANPAR®Categories: Heterocyclic Compounds, 1-Ring
  6. Drug

    Efzofitimod

    go.drugbank.com/drugs/DB16453
    Investigational

    It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response in inflammatory disease states. … Efzofitimod (ATYR1923) is a fusion protein comprised of the immuno-modulatory domain of histidyl tRNA synthetase fused to the FC region of a human antibody.

    Synonyms: Human IgG1Fc- iMod domain (amino acids 2-60) of human HARS fusion protein
  7. Drug

    Cindunistat

    go.drugbank.com/drugs/DB20593
    Experimental

    Cindunistat is a small molecule drug. Cindunistat has a monoisotopic molecular weight of 219.1 Da.

    Categories: Nitric Oxide Synthase Type II, antagonists & inhibitors
  8. Drug

    1alpha,24S-Dihydroxyvitamin D2

    go.drugbank.com/drugs/DB06117
    Experimental

    LR-103 is a naturally occurring D-hormone that is produced by the kidneys from vitamin D. LR-103 is one of the D-hormones produced from Hectorol. … It is developed for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease (CKD). Studies have shown LR-103 has the same potency as calcitriol, but much lower toxicity.

    Categories: Vitamin D and Analogues
  9. Drug

    Phthalylsulfathiazole

    go.drugbank.com/drugs/DB13248
    Approved

    Phthalylsulfathiazole is a broad spectrum antibiotic which is part of the drug class, sulfonamides. It was used as an antibiotic for bowel surgery, and for infections of the colon [A175006].

    Categories: Heterocyclic Compounds, 1-Ring
  10. Drug

    Ramoplanin

    go.drugbank.com/drugs/DB04952
    Experimental

    Ramoplanin is a novel glycolipodepsipeptide antibiotic under development for the treatment of CDAD.