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Displaying results 5531 - 5540 of 10000 in total
  1. Drug

    Rezatapopt

    go.drugbank.com/drugs/DB18980
    Investigational

    Rezatapopt is under investigation in clinical trial NCT04585750 (The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)).

    Synonyms: 4-[[3-[4-[[(3S,4R)-3-Fluoro-1-methyl-4-piperidinyl]amino]-1-(2,2,2-trifluoroethyl)-1H-indol-2-yl]-2-propyn-1-yl]amino]-3-methoxy-N-methylbenzamide, Benzamide, 4-[[3-[4-[[(3S,4R)-3-fluoro-1-methyl-4-piperidinyl]amino]-1-(2,2,2-trifluoroethyl)-1H-indol-2-yl]-2-propyn-1-yl]amino]-3-methoxy-N-methyl-
  2. Drug

    Sevasemten

    go.drugbank.com/drugs/DB18983
    Investigational

    Sevasemten is under investigation in clinical trial NCT05291091 (Phase 2 Study of EDG-5506 in Becker Muscular Dystrophy (GRAND CANYON)).

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: 2-[(5-fluoropyridin-3-yl)methyl]-6-[2-(2,2,2- trifluoroethoxy)pyrimidin-5-yl]pyridazin-3(2H)-one
  3. Drug

    Survodutide

    go.drugbank.com/drugs/DB18989
    Investigational

    Survodutide is under investigation in clinical trial NCT06077864 (A Study to Test the Effect of Survodutide (BI 456906) on Cardiovascular Safety in People With Overweight or Obesity (SYNCHRONIZE™ - CVOT

  4. Drug

    Pegtarviliase

    go.drugbank.com/drugs/DB18999
    Investigational

    Pegtarviliase is under investigation in clinical trial NCT05154890 (A Multiple Ascending Dose Study of ACN00177 (Pegtarviliase) in Subjects With CBS Deficiency).

  5. Drug

    Supinoxin

    go.drugbank.com/drugs/DB19010
    Investigational

    Supinoxin is under investigation in clinical trial NCT02003092 (RX-5902 Treatment of Subjects With Triple Negative Breast Cancer).

    Synonyms: 1-piperazinecarboxamide, 4-(3,5-dimethoxyphenyl)-n-(7-fluoro-3-methoxy-2-quinoxalinyl)-, 1-(3,5-dimethoxyphenyl)-4-((6-fluoro-2-methoxyquinoxalin-3-yl)aminocarbonyl) piperazineCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  6. Drug

    Efruxifermin

    go.drugbank.com/drugs/DB19012
    Investigational

    Efruxifermin is under investigation in clinical trial NCT06215716 (A Study Evaluating Efruxifermin in Subjects With Non-cirrhotic Nonalcoholic Steatohepatitis (Nash)/metabolic Dysfunction-associated Steatohepatitis

    Synonyms: Immunoglobulin g1 (human .gamma.1-chain c-region c-terminal fragment) fusion protein with peptide linker (ggggs)3 fusion protein with fibroblast growth factor 21 (98-arginine,171-glycine,180-glutamic acid, Immunoglobulin g (synthetic human constant domain fc fragment) fusion protein with fibroblast growth factor 21 (98-arginine,171-glycine,180-glutamic acid) (human mutant clone amg876)
  7. Drug

    L-377202

    go.drugbank.com/drugs/DB19022
    Investigational

    L-377202 is under investigation in clinical trial NCT00987753 (Study Evaluating the Safety and Tolerability of L-377202).

    Synonyms: 5-((2s,4r)-2-(((1s)-2-(((1s)-2-(((1s)-2-(((1s)-4-amino-1-(((1s)-1-(hydroxymethyl)-2-(((1s)-1-(((2s,3s,4s,6r)-3-hydroxy-2-methyl-6-(((1s,3s)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4, 5,12-NAPHTHACENEDIONE, 10-((3-(((4R)-1-(4-CARBOXY-1-OXOBUTYL)-4-HYDROXY-L-PROLYL-L-ALANYL-L-SERYL-(2S)-2-CYCLOHEXYLGLYCYL-L-GLUTAMINYL-L-SERYL-L-LEUCYL)AMINO)-2,3,6-TRIDEOXY-.ALPHA.
  8. Drug

    Atuliflapon

    go.drugbank.com/drugs/DB19029
    Investigational

    Atuliflapon is under investigation in clinical trial NCT05251259 (Study to Assess the Efficacy and Safety of Atuliflapon in Moderate-to-severe Uncontrolled Asthma).

    Synonyms: (1r,2r)-2-(4-(3-methyl-1h-pyrazol-5-yl)benzoyl)-n-(4-oxo-6,7-dihydro-5h-pyrazolo(1,5-a)pyrazine-3-yl)cyclohexanecarboxamide, Cyclohexanecarboxamide, 2-(4-(5-methyl-1h-pyrazol-3-yl)benzoyl)-n-(4,5,6,7-tetrahydro-4-oxopyrazolo(1,5-a)pyrazin-3-yl)-, (1r,2r)-Categories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Atuzaginstat

    go.drugbank.com/drugs/DB19030
    Investigational

    Atuzaginstat is under investigation in clinical trial NCT03823404 (GAIN Trial: Phase 2/3 Study of COR388 in Subjects With Alzheimer's Disease).

    Synonyms: N-((3s)-7-amino-2-oxo-1-(2,3,6- trifluorophenoxy)heptan-3-yl)cyclopentanecarboxamide, Cyclopentanecarboxamide, n-((1s)-5-amino-1-(2-(2,3,6-trifluorophenoxy)acetyl)pentyl)-
  10. Drug

    Mevidalen

    go.drugbank.com/drugs/DB19034
    Investigational

    Mevidalen is under investigation in clinical trial NCT03305809 (A Study of LY3154207 in Participants With Dementia Due to Lewy Body Dementia (LBD) Associated With Idiopathic Parkinson's Disease (PD) or

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 2-(2,6-dichlorophenyl)-1-((1s,3r)-3-(hydroxymethyl)-5-(3-hydroxy-3-methylbutyl)-1-methyl-3,4-dihydroisoquinolin-2(1h)-yl)ethanone, Ethanone, 2-(2,6-dichlorophenyl)-1-((1s,3r)-3,4-dihydro-3-(hydroxymethyl)-5-(3-hydroxy-3-methylbutyl)-1-methyl-2(1h)-isoquinolinyl)-