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NNZ-2591
go.drugbank.com/drugs/DB15601InvestigationalNNZ-2591 (cyclo-L-glycyl-L-2-allylproline)[A189390] is an investigational synthetic analog of cyclic glycine-proline (cGP), a breakdown product of human insulin-like growth factor 1 (IGF-1), that has been … It was granted Orphan Drug Designation by the FDA in October 2019[L11103] and was granted a patent by the European Patent Office in December 2019.
Synonyms: Pyrrolo(1,2-a)pyrazine-1,4-dione, hexahydro-8a-(2-propenyl)-, (8aR)-Virginiamycin
go.drugbank.com/drugs/DB11476ExperimentalVet approvedAccording to a USDA study, antibiotics can save as much as 30% in feed costs among young swine. … Virginiamycin is a streptogramin antibiotic similar to pristinamycin and quinupristin/dalfopristin. It is a combination of pristinamycin IIA and virginiamycin S1.
CR665
go.drugbank.com/drugs/DB05155ExperimentalCR665 is the lead clinical development candidate from a series of highly selective peripheral kappa opioid receptor agonists. … In preclinical studies, CR665 was highly selective for the peripheral kappa opioid receptor. Preclinical animal studies suggest that CR665 is a potent analgesic compound.
Recombinant human plasma gelsolin
go.drugbank.com/drugs/DB15746InvestigationalPlasma gelsolin (pGSN) is a protein found in the blood of healthy individuals which scavenges compounds left over from damaged tissues.
NS-3728
go.drugbank.com/drugs/DB05835ExperimentalNS3728 is an orally active chloride channel blocker for the treatment of cancer.
CP-122721
go.drugbank.com/drugs/DB05421ExperimentalCP-122721, neurokinin 1 (NK1) antagonist is developed by Pfizer to treat depression, emesis, and inflammatory diseases including asthma and irritable bowel syndrome.
Macelignan
go.drugbank.com/drugs/DB14129InvestigationalMacelignan is an NSAID with antioxidant, free radical scavenging, and neuroprotective activities.
Go-6976
go.drugbank.com/drugs/DB17029ExperimentalAn inhibitor of calcium-dependent isoforms of protein kinase C.[A253002,A253007]
Synonyms: 12h-indolo(2,3-a)pyrrolo(3,4-c)carbazole-12-propanenitrile, 5,6,7,13-tetrahydro-13-methyl-5-oxo-N-oleoyldopamine
go.drugbank.com/drugs/DB17036ExperimentalN-oleoyldopamine (OLDA) is an amide of dopamine and oleic acid.[A253042]
PI-103
go.drugbank.com/drugs/DB17046ExperimentalPI-103 is an inhibitor of p110α of class I PI3K.[A253092]