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Tetracycline
go.drugbank.com/drugs/DB00759ApprovedInvestigationalVet approvedWithdrawnThe FDA withdrew its approval for the use of all liquid oral drug products formulated for pediatric use containing tetracycline in a concentration greater than 25 mg/ml. … It exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit and blocking incoming aminoacyl tRNA from binding to the ribosome acceptor site.
Products: PIPERACILLINA E TAZOBACTAM EGVerapamil
go.drugbank.com/drugs/DB00661ApprovedInvestigationalinto therapy in the early 1960s. … Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina,[L8791] and was the first calcium channel antagonist to be introduced
Mixtures: Trandolapril and Verapamil Hydrochloride ER, Trandolapril and Verapamil Hydrochloride ERInternational brands: Verogalid ERLoperamide
go.drugbank.com/drugs/DB00836ApprovedInvestigationalLoperamide is an anti-diarrheal agent that is available as an over-the-counter product for treating diarrhea.[L42785] The drug was first synthesized in 1969 and used medically in 1976. … [A251610] It is a highly lipophilic synthetic phenylpiperidine opioid that works by binding to mu-opioid receptors on intestinal muscles to decrease intestinal motility and electrolyte loss.
Mixtures: Meds on the Go, Doc in the Box All Day SupplyProducts: LOPERAMIDE EG, IMODIUM NDoxazosin
go.drugbank.com/drugs/DB00590ApprovedInvestigational[A180649] It is marketed by Pfizer and was initially approved by the FDA in 1990.[L7285] … Doxazosin is an alpha-1 antagonist used for the treatment of benign prostatic hypertrophy (BPH) symptoms and hypertension.
Categories: Drugs Used in Benign Prostatic HypertrophyProducts: DOXAZOSINA EGMetoprolol
go.drugbank.com/drugs/DB00264ApprovedInvestigational[T274] To this date, it is one of the preferred beta-blockers in general clinical guidelines and it is widely prescribed in the Netherlands, New Zealand, and the US. … [A175162] Metoprolol was developed since 1969 by US Pharmaceutical Holdings I and FDA approved in 1978.[L5527]
Products: METOPROLOLO EG, Metoprolol Succinate ERRamipril
go.drugbank.com/drugs/DB00178ApprovedInvestigationalIt is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. … Ramipril may be used in the treatment of hypertension, congestive heart failure, nephropathy, and to reduce the rate of death, myocardial infarction and stroke in individuals at high risk of cardiovascular
Mixtures: RAMIPRIL E AMLODIPINA EG, RAMIPRIL E AMLODIPINA EGCategories: Agents Acting on the Renin-Angiotensin SystemLetrozole
go.drugbank.com/drugs/DB01006ApprovedInvestigationalLetrozole, or CGS 20267, is an oral non-steroidal type II aromatase inhibitor first described in the literature in 1990. … [A190546] Letrozole was granted FDA approval on 25 July 1997.[L11623]
Products: LETROZOLO EG, SOLESTRASA-INOlmesartan
go.drugbank.com/drugs/DB00275ApprovedInvestigationalOlmesartan also affects the renin-angiotensin aldosterone system (RAAS), which plays an important role in hemostasis and regulation of kidney, vascular, and cardiac functions. … In particular, heart failure is associated with chronic activation of RAAS, leading to inappropriate fluid retention, vasoconstriction, and ultimately a further decline in left ventricular function.
Mixtures: OLMESARTAN E AMLODIPINA EG, OLMESARTAN E AMLODIPINA EGCategories: Agents Acting on the Renin-Angiotensin SystemMesalazine
go.drugbank.com/drugs/DB00244ApprovedInvestigationalAn anti-inflammatory agent, structurally related to the salicylates and non-steroidal anti-inflammatory drugs like acetylsalicylic acid, which is active in inflammatory bowel disease [A174022]. … the risk of colorectal cancer in conditions like ulcerative colitis is maintained.
Products: MESALAZINA EG, MESALAZINA EG STADASodium chloride
go.drugbank.com/drugs/DB09153ApprovedInvestigationalVet approvedSodium chloride is the primary salt in seawater and in the extracellular fluid of many multicellular organisms. It is listed on the World Health Organization Model List of Essential Medicines. … Sodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions.
Mixtures: EN DEXTROSA 5%, DEXTROSA AL 5% EN SOLUCION SALINAProducts: CLORURO DE SODIO AL 0.9% EN AGUA INYECTABLE, CLORURO DE SODIO AL 0.9% EN AGUA INYECTABLE BAXTER