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Displaying results 551 - 560 of 10000 in total
  1. Drug

    Pitavastatin

    go.drugbank.com/drugs/DB08860
    ApprovedInvestigational

    More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,[A181421] which catalyzes the conversion of HMG-CoA to mevalonic acid. … [A181087, A181406] Pitavastatin and other drugs from the statin class of medications including [atorvastatin], [pravastatin], [rosuvastatin], [fluvastatin], and [lovastatin] are considered first-line

    Products: LIVAZO 1MG FTA, PITAS 1MG FILM TABLET, TABLET, 30 ADET
  2. Drug

    Propantheline

    go.drugbank.com/drugs/DB00782
    Approved

    A muscarinic antagonist used as an antispasmodic, in rhinitis, in urinary incontinence, and in the treatment of ulcers. At high doses it has nicotinic effects resulting in neuromuscular blocking.

    Products: Pro-banthine Tablets 7.5 mg, Propanthel Tab 15mg
  3. Drug

    Docusate

    go.drugbank.com/drugs/DB11089
    Approved

    Recently there has been pressure to stop prescribing docusate as it has been identified as an ineffective medicine[A176972,A176987,L5912]. … Additionally, it does not appear to lessen symptoms associated with constipation such as abdominal cramps. Still docusate is available in over-the-counter products as a common laxative.

    Mixtures: Laxatif De Sene Et Docusate De Sodium, E-Vac PlusProducts: EX-lax Stool Softener - Tab 100 mg, H E B Stool Softener laxative
  4. Drug

    Mepivacaine

    go.drugbank.com/drugs/DB00961
    ApprovedInvestigationalVet approved

    It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route.

    Mixtures: MEPISEAL-ESynonyms: N-(2,6-Dimethylphenyl)-1-methyl-2-piperidinecarboxamide, N-(2,6-Dimethylphenyl)-1-methylpiperidine-2-carboxamide
  5. Drug

    Guanethidine

    go.drugbank.com/drugs/DB01170
    ApprovedWithdrawn

    It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues. … An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves.

    Synonyms: 2-(1-N,N-Heptamethyleneimino)ethylguanidine, N-(2-Perhydroazocin-1-ylethyl)guanidineProducts: Guanethidine 10 Tab 10mg, Apo Guanethidine Sulfate Tab 10mg
  6. Drug

    Oxygen

    go.drugbank.com/drugs/DB09140
    ApprovedInvestigationalVet approved

    Oxygen is an element displayed by the symbol O, and atomic number 8. It is an essential element for human survival. Decreased oxygen levels may be treated with medical oxygen therapy. … an attempt to oxygenate the lungs.

    Mixtures: Co-NE-O2-N2 Mixture, Oxygen In Helium MixProducts: Ez-OX, EZ-Ox
  7. Drug

    Methyldopa

    go.drugbank.com/drugs/DB00968
    ApprovedInvestigational

    [A231784] It is an analog of DOPA (3,4‐hydroxyphenylanine), and it is a prodrug, meaning that the drug requires biotransformation to an active metabolite for therapeutic effects. … Since then, methyldopa was largely replaced by newer, better-tolerated antihypertensive agents;[A231784] however, it is still used as monotherapy [L32614] or in combination with [hydrochlorothiazide].

    Products: Aldomet Tab 125mg, Dopamet Tab 125mg
  8. Drug

    Emicizumab

    go.drugbank.com/drugs/DB13923
    ApprovedInvestigational

    Emicizumab was originated as an improved form of hBS23 and it was approved on November 16, 2017.[A31279, L1016] It was created by Chugai Pharmaceuticals Co. … The ability of Emicizumab to bind to all these three different factors allows it to overcome immunogenicity and unstable hemostatic efficacy produced by previous Factor VII agents.

    Products: HEMLIBRA® 30 MG/ML SOLUCION INYECTABLE, HEMLIBRA® 150 MG/ML SOLUCIÓN INYECTABLE
  9. Drug

    Eribulin

    go.drugbank.com/drugs/DB08871
    ApprovedInvestigational

    Eribulin is also being investigated for use in the treatment of advanced solid tumors [A7439]. … Eribulin is a microtubule inhibitor indicated for the treatment of patients with metastatic breast cancer who have previously received at least two chemotherapeutic regimens for the treatment of metastatic

    Products: ERIBULINA EG, HALAVEN 0.5 mg/ml solution for injection
  10. Drug

    Ranibizumab

    go.drugbank.com/drugs/DB01270
    ApprovedInvestigational

    [A246399] Ranibizumab was initially approved by the FDA in 2006 [A2301] and by the European Commission (EC) in 2007.[L41429] It is marketed under the brand names LUCENTIS and SUSVIMO. … [L41399] In August 2022, other biosimilars CIMERLI, RAIVISIO, and RANOPTO were approved by the FDA, EC, and Health Canada respectively.[L42625,L43513,L49141]

    Products: LUCENTIS 10 MG/ML SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE, LUCENTIS® 10 MG /ML SOLUCION INYECTABLE