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Tamoxifen
go.drugbank.com/drugs/DB00675ApprovedInvestigational[A1025,L7799,L7802] Tamoxifen is used alone or as an adjuvant in these treatments. … Tamoxifen is a non-steroidal antiestrogen used to treat estrogen receptor positive breast cancers as well as prevent the incidence of breast cancer in high risk populations.
Categories: UGT2B7 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: TAMOXIFEN AL 20, TAMOXIFEN AL 30Hydroxyzine
go.drugbank.com/drugs/DB00557ApprovedInvestigational[A1257,A187589] It was first developed in 1955,[A189726] and has since remained a relatively common treatment for allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus … [L9677] The active metabolite of hydroxyzine, [cetirizine], is also available as an active ingredient in allergic medications, and is responsible for much of its hydroxyzine's antihistaminic effect.
Products: AA PHARMA HYDROXYZINE CAPSULE 10 mg, AA PHARMA HYDROXYZINE CAPSULE 25 mgNizatidine
go.drugbank.com/drugs/DB00585ApprovedA histamine H2 receptor antagonist with low toxicity that inhibits gastric acid secretion. The drug is used for the treatment of duodenal ulcers.
Products: Axid ArMorphine
go.drugbank.com/drugs/DB00295ApprovedInvestigational[A176035] It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. … [A176050] Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength such as [codeine], [fentanyl], [methadone], [hydrocodone], [hydromorphone], [meperidine
Products: MORPHIN AL 10 RETARD, MORPHIN AL 30 RETARDDarunavir
go.drugbank.com/drugs/DB01264ApprovedInvestigationalDarunavir is a protease inhibitor used with other HIV protease inhibitor drugs as well as [ritonavir] for the effective management of HIV-1 infection. … [L9227] As a second-generation protease inhibitor, darunavir is designed to combat resistance to standard HIV therapy.[A2278,A2281] It was initially approved by the FDA in 2006.
Products: DARUNAVIR AL 400MG FTA, DARUNAVIR AL 600MG FTAImatinib
go.drugbank.com/drugs/DB00619ApprovedInvestigational[A249305] It was deemed a "miracle drug" due to its clinical success, as oncologist Dr. … Imatinib is a small molecule kinase inhibitor that revolutionized the treatment of cancer, particularly chronic myeloid leukemia, in 2001.
Products: IMATINIB AL 100 MG FTA, IMATINIB AL 400 MG FTAMagnesium sulfate
go.drugbank.com/drugs/DB00653ApprovedInvestigationalVet approvedA small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. … It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions.
Mixtures: Calcium Lactate Et Magnesium SulfateProducts: SULFATO DE MAGNESIO AL 20%, SULFATO DE MAGNESIO AL 20% AMPOLLA X 10 ML SOLUCION INYECTABLEEdoxaban
go.drugbank.com/drugs/DB09075ApprovedInvestigationalEdoxaban is a member of the Novel Oral Anti-Coagulants (NOACs) class of drugs, and is a rapidly acting, oral, selective factor Xa inhibitor. … (PE) following 5-10 days of initial therapy with a parenteral anticoagulant.
Products: Ag-edoxabanDesvenlafaxine
go.drugbank.com/drugs/DB06700ApprovedInvestigational[A261271] Desvenlafaxine has a very similar pharmacological, efficacy, and safety profile as [venlafaxine]. … [L6016,A261271] MDD is a highly prevalent psychiatric disorder, with a lifetime prevalence estimate of 16% in the US alone and 12.8% in Europe.
Products: Ag-desvenlafaxineOctasulfur
go.drugbank.com/drugs/DB09353ApprovedSulfur seems to have an antibacterial activity. It has been also used for acne. … Sulfur is a chemical element that is present in all living tissues. The most commonly used form of pharmaceutical sulfur is Octasulfur (S8).
Mixtures: EGOPSORYL TA GEL, EGOPSORYL TA GELProducts: Epionce Purifying Spot Gel, Sul-ray Acne Treatment Sop 5%