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Displaying results 5591 - 5600 of 10000 in total
  1. Drug

    Synephrine

    go.drugbank.com/drugs/DB09203
    Investigational

    The similarity of naming between m-synephrine and the unsubstituted form, synephrine, is a source of some confusion however m-synephrine refers to a related drug more commonly known as phenylephrine. … While the compounds share some chemical and pharmacological similarities, they are in fact distinct chemical entities.

    Categories: Adrenergic and Dopaminergic Agents, Decongestants and Antiallergics
  2. Drug

    Dexamethasone isonicotinate

    go.drugbank.com/drugs/DB11487
    ExperimentalVet approved

    Dexamethasone isonicotinate is an anti-inflammatory, anti-allergic glucocorticoid that can be administered orally, by inhalation, topically, and parenterally. … Its unintended mineralocorticoid action may cause salt and water retention.

    Categories: Hormones, Hormone Substitutes, and Hormone Antagonists
  3. Drug

    Pirlindole

    go.drugbank.com/drugs/DB09244
    Experimental

    The antidepressant efficacy and safety of pirlindole have been demonstrated in numerous studies and, supported by many years of clinical experience in the treatment of depression. … It was developed and is currently used as an antidepressant in Russia. Its chemical structure is similar to metralindole, and it also shares pharmacological properties with this drug.

    Synonyms: 2,3,3a,4,5,6-Hexahydro-8-methyl-1H-pyrazino(3,2,1-jk)carbazole
  4. Drug

    Lubazodone

    go.drugbank.com/drugs/DB09196
    Experimental

    Lubazodone (YM-992, YM-35,995) is an arylpiperazine antidepressant which was being developed as a treatment for depression and obsessive compulsive disorder, and reached phase II clinical trials, but was … It acts as a serotonin reuptake inhibitor and 5-HT2A receptor antagonist.

  5. Drug

    Sizofiran

    go.drugbank.com/drugs/DB13128
    Investigational

    A beta-D-glucan obtained from the Aphyllophoral fungus Schizophyllum commune. It is used as an immunoadjuvant in the treatment of neoplasms, especially tumors found in the stomach.

  6. Drug

    Denufosol

    go.drugbank.com/drugs/DB04983
    Investigational

    The drug was also evaluated in the treatment of retinal detachment and other diseases of the retina. Denufosol has not gained FDA approval, and clinical trials with this drug have ceased since 2011. … Denufosol was an inhaled drug used for the treatment of cystic fibrosis (CF), showing various improvements in lung function during a phase III clinical trial.

    Categories: Nucleic Acids, Nucleotides, and Nucleosides
  7. Drug

    Velafermin

    go.drugbank.com/drugs/DB06493
    Investigational

    Velafermin was investigated as a potential therapy for the prevention and treatment of oral mucositis by fostering the regeneration and repair of the cells lining the gastrointestinal tract. … Velafermin was a novel investigational protein therapeutic, also known as fibroblast growth factor-20 (FGF-20), which promotes both epithelial and mesenchymal cell proliferation in vitro and has demonstrated

    Categories: Amino Acids, Peptides, and Proteins, Intercellular Signaling Peptides and Proteins
  8. Drug

    Endostatin

    go.drugbank.com/drugs/DB06423
    Investigational

    Categories: Amino Acids, Peptides, and Proteins, Intercellular Signaling Peptides and Proteins
  9. Drug

    Vicriviroc

    go.drugbank.com/drugs/DB06652
    Investigational

    Vicriviroc, also known as SCH 417690 and SCH-D, is currently in clinical trials for the management of HIV-1. … This drug was developed by Schering-Plough.

  10. Drug

    Zofin

    go.drugbank.com/drugs/DB16519
    Investigational

    Zofin, previously known as Organicell Flow, is a nanoparticle-based therapeutic derived from perinatal sources which is manufactured in a way that retains the naturally occurring microRNAs without the