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Transcrocetinate
go.drugbank.com/drugs/DB05974InvestigationalVitamin A-analog that increases diffusivity of oxygen in aqueous solutions, including plasma.
Categories: Compounds used in a research, industrial, or household settingSynonyms: 8,8'-diapo-ψ,ψ-carotenedioic acidPalivizumab
go.drugbank.com/drugs/DB00110ApprovedInvestigationalSynagis is a composite of human (95%) and murine (5%) antibody sequences. … Palivizumab is expressed from a stable murine (mouse) myeloma cell line (NS0).
Categories: Respiratory Syncytial Virus Anti-F Protein Monoclonal AntibodyProducts: SYNAGIS 100 MG/1 ML IM ENJEKSIYONLUK ÇÖZELTI IÇEREN FLAKON,1 ADET, SYNAGIS® 50 MGOmacetaxine mepesuccinate
go.drugbank.com/drugs/DB04865ApprovedInvestigationalWithdrawnOmacetaxine mepesuccinate (formerly known as HHT or Homoharringtonine), is a cephalotaxine ester and protein synthesis inhibitor with established clinical activity as a single agent in hematological malignancies … Omacetaxine mepesuccinate is synthesized from cephalotaxine, which is an extract from the leaves of the plant, Cephalotaxus species.
Categories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds with 4 or More RingsSynonyms: (2'R,3S,4S,5R)-(−)-homoharringtonine, 1-[(1S,3aR,14bS)-2-Methoxy-1,5,6,8,9,14b-hexahydro-4H-cyclopenta[a][1,3]dioxolo[4,5-H]pyrrolo[2,1-b][3]benzazepin-1-yl] 4-methyl (2R)-2-hydroxy-2-(4-hydroxy-4-methylpentyl)butanedioateMevociclib
go.drugbank.com/drugs/DB21454InvestigationalMevociclib is a small molecule drug. The usage of the INN stem '-ciclib' in the name indicates that Mevociclib is a cyclin dependant kinase inhibitor. … Mevociclib is under investigation in clinical trial NCT03134638 (A Study of SY-1365 in Adult Patients With Advanced Solid Tumors). Mevociclib has a monoisotopic molecular weight of 586.26 Da.
Categories: Heterocyclic Compounds, 1-RingArtemotil
go.drugbank.com/drugs/DB13851ApprovedArtemotil, also known as β-arteether, is a semi-synthetic derivative of artemisinin and a fast acting blood schizonticide specifically indicated for the treatment of chloroquine-resistant _Plasmodium falciparum
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesVibecotamab
go.drugbank.com/drugs/DB18872InvestigationalVibecotamab is under investigation in clinical trial NCT05285813 (A Phase II Study of Vibecotamab (Xmab14045) for MRD- Positive AML and MDS After Hypomethylating Agent Failure).
Synonyms: Anti-cd123 x anti-cd3 bispecific antibody xmab14045Peptide-T
go.drugbank.com/drugs/DB19279InvestigationalPeptide-T is under investigation in clinical trial NCT00000392 (Phase II Study of the Efficacy of Peptide T in Hiv-positive Individuals With Cognitive Impairment.).
Synonyms: L-threonine, l-alanyl-l-seryl-l-threonyl-l-threonyl-l- threonyl-l-asparaginyl-l-tyrosyl-, Peptide TEtilefrine
go.drugbank.com/drugs/DB08985ApprovedWithdrawnEtilefrine is an adrenergic agonist that appears to interact with beta-1 and some alpha-adrenergic receptors. It has been used as a vasoconstrictor agent.
Categories: Adrenergic beta-1 Receptor Agonists, Compounds used in a research, industrial, or household settingProducts: EFFORTIL® AMPOLLAS, EFFORTIL LOESUNG Z TROPFENFenticonazole
go.drugbank.com/drugs/DB13434InvestigationalFenticonazole has a broad spectrum of antimycotic activity against dermatophytes and yeasts.[A275048]
Categories: Heterocyclic Compounds, 1-RingProducts: Lomexin 2%-Creme, JİNOMED 600 MG OVÜL, 2 OVÜLAlitretinoin
go.drugbank.com/drugs/DB00523ApprovedTretinoin, also known as retinoic acid and derived from maternal vitamin A, is essential for normal growth; and embryonic development. An excess of tretinoin can be teratogenic. … It is used in the treatment of psoriasis; acne vulgaris; and several other skin diseases. It has also been approved for use in promyelocytic leukemia (leukemia, promyelocytic, acute).
Mixtures: Clindamycin 1% / Niacinamide 4% / Tretinoin 0.05%Categories: Vitamin A, P-glycoprotein substrates