DB05974InvestigationalSmall molecule
Vitamin A-analog that increases diffusivity of oxygen in aqueous solutions, including plasma.
- Mechanism
- Curator reviewed
Trans sodium crocetinate is a novel drug, which has been shown to increase whole-body oxygen consumption during hemorrhagic shock. It works by increasing the diffusion rate of oxygen through plasma rather than on a specific symptom of hemorrhagic shock and has been suggested as a general treatment for hypoxemia. Thus it could also be beneficial for treating respiratory insufficiencies.
- Primary indication
- Investigated for use/treatment in cancer/tumors (unspecified), hemorrhage, hypoxia, respiratory failure, and strokes.Curator reviewed
- Formula / weight
- C20H24O4 · 328.408 g/mol (avg)
- Also known as
- Crocetin · trans-crocetin · transcrocetin
Resolves to
Clinical / RWD
Structure
InChIKey
PANKHBYNKQNAHN-MQQNZMFNSA-NSMILESC\C(\C=C\C=C(/C)C(O)=O)=C/C=C/C=C(\C)/C=C/C=C(\C)C(O)=OTargets
What you can answer from here — as of September 20, 2026
Which drugs share a target with Transcrocetinate, and which of those have an active Phase 3 trial?
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