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Silibinin
go.drugbank.com/drugs/DB09298InvestigationalSilibinin is presented as a mixture of two diastereomers, silybin A and silybin B, which are found in an approximately equimolar ratio. … Both in vitro and animal research suggest that silibinin has hepatoprotective (antihepatotoxic) properties that protect liver cells against toxins.
Categories: Compounds used in a research, industrial, or household settingQuinacrine
go.drugbank.com/drugs/DB01103InvestigationalAn acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. … It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
Vimseltinib
go.drugbank.com/drugs/DB17520ApprovedInvestigationalA265035] It is intended to provide a safer alternative to [pexidartinib], a previously approved CSF1R inhibitor associated with significant liver toxicity - the greater selectivity of vimseltinib results in … [L52230,A265035] Vimseltinib - under the brand name Romvimza - was approved by the FDA in February 2025 for the treatment of tenosynovial giant cell tumours for which surgical resection is not appropriate
Nelotanserin
go.drugbank.com/drugs/DB12555InvestigationalNelotanserin has been used in trials studying the treatment of Lewy Body Dementia, Visual Hallucinations, Dementia With Lewy Bodies, and REM Sleep Behavior Disorder. … It increases non-REM sleep, the most restorative phase of the sleep cycle, without sacrificing REM or dream sleep.
MVA-SARS-2-S
go.drugbank.com/drugs/DB16432InvestigationalMVA is a highly attenuated poxvirus vector[A226603] that has a high-level of biological safety due to its quality of being a non-replicating virus in mammalian hosts[L30458] and is used to develop vaccines
Obinepitide
go.drugbank.com/drugs/DB05045ExperimentalThese hormones are known to play a role in the regulation of food intake and appetite in man as satiety signal from the GI-tract to the CNS. … In obinepitide, the properties of both of these hormones have been implanted into a single molecule.
Typhoid Vaccine Live
go.drugbank.com/drugs/DB11050ApprovedInvestigationalThe vaccine prevents the development of typhoid fever, an acute, febrile enteric disease caused by *Salmonella typhi* by inducing a local immune response in the intestinal tract.
Liposomal prostaglandin E1
go.drugbank.com/drugs/DB05391InvestigationalLiposome-encapsulated form of prostaglandin E1 (Liprostin) is known to be a potent vasodilator and platelet inhibitor as well as an anti-inflammatory and anti-thrombotic agent. … The liposomal formulation of PGE-1 changes the drug’s dynamics and improve its therapeutic index in ways that PGE-1 alone could not achieve.
Synonyms: Liposomal prostaglandin E1