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Displaying results 5661 - 5670 of 10000 in total
  1. Drug

    anti-alpha5Beta1-integrin antibody

    go.drugbank.com/drugs/DB05870
    Experimental

    Integrins are important adhesion molecules that regulate tumor and endothelial cell survival, proliferation and migration. … The integrin alpha5beta1 has been shown to play a critical role during angiogenesis. anti-alpha5beta1 integrin antibody inhibits angiogenesis, including vessel formation induced by vascular endothelial

  2. Drug

    Cholesterol

    go.drugbank.com/drugs/DB04540
    ApprovedInvestigationalWithdrawn

    The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.

  3. Drug

    Edodekin alfa

    go.drugbank.com/drugs/DB15631
    Investigational

    , or Cannot Be Removed by Surgery). … Edodekin alfa is under investigation in clinical trial NCT01468896 (Cetuximab and Recombinant Interleukin-12 in Treating Patients With Squamous Cell Carcinoma of the Head and Neck That Is Recurrent, Metastatic

    Categories: Amino Acids, Peptides, and Proteins, Intercellular Signaling Peptides and Proteins
  4. Target

    Angiopoietin-1

    go.drugbank.com/bio_entities/BE0010681
    TargetHumans

    Implicated in endothelial developmental processes later and distinct from that of VEGF. … Plays an important role in the regulation of angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance

    Synonyms: ANG-1
  5. Drug

    AT3022

    go.drugbank.com/drugs/DB05172
    Experimental

    AT3022, the Altea Therapeutics’s fentanyl citrate transdermal patch designed to provide safe and rapid management of moderate to severe chronic pain.

  6. Drug

    N-Methylmesoporphyrin

    go.drugbank.com/drugs/DB01911
    Experimental

    These are compounds containing a fundamental skeleton of four pyrrole nuclei united through the alpha-positions by four methine groups to form a macrocyclic structure.

  7. Indication

    Invasive Meningococcal Infection caused by Neisseria meningitidis serogroup Y

    go.drugbank.com/conditions/DBCOND0093729
    Drugs: Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine · Meningococcal polysaccharide vaccine group Y · Neisseria meningitidis group A capsular polysaccharide tetanus toxoid conjugate antigen · Neisseria meningitidis group y capsular polysaccharide diphtheria toxoid conjugate antigen
  8. Drug

    Nicotinamide adenine dinucleotide phosphate

    go.drugbank.com/drugs/DB03461
    Experimental

    It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) … A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate.

    Categories: Enzymes and Coenzymes, Nucleic Acids, Nucleotides, and Nucleosides
  9. Drug

    Lanoteplase

    go.drugbank.com/drugs/DB06245
    Experimental

    Categories: Enzymes and Coenzymes, Amino Acids, Peptides, and Proteins
  10. Drug

    Bromus secalinus pollen

    go.drugbank.com/drugs/DB10836
    Approved

    Bromus secalinus pollen is the pollen of the Bromus secalinus plant. Bromus secalinus pollen is mainly used in allergenic testing.

    Mixtures: Mixture of Twenty-Two Standardized and Non-Standardized Grasses