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Lovotibeglogene autotemcel
go.drugbank.com/drugs/DB18680ApprovedInvestigational[A262736,L49256] On December 8, 2023, lovotibeglogene autotemcel was approved by the FDA under the brand name Lyfgenia for the treatment of sickle cell disease (SCD) in patients ages 12 and older who … [L49266] It was approved alongside [exagamglogene autotemcel] (Casgevy), another gene therapy, with the two treatments comprising the first cell-based gene therapies for the treatment of SCD in patients
Roledumab
go.drugbank.com/drugs/DB16317InvestigationalRoledumab is under investigation in clinical trial NCT02287896 (Pharmacokinetics and Safety of Roledumab in Rhd-negative Pregnant Women Carrying an Rhd-positive Foetus).
Tesnatilimab
go.drugbank.com/drugs/DB16377InvestigationalTesnatilimab is under investigation in clinical trial NCT04655807 (A Study of JNJ-64304500 as Add-on Therapy in Participants With Active Crohn's Disease).
ZEN-3694
go.drugbank.com/drugs/DB22031InvestigationalZEN-3694 is under investigation in clinical trial NCT04840589 (Testing the Combination of ZEN003694 and Nivolumab With or Without Ipilimumab in Solid Tumors).
Synonyms: BETi ZEN-3694Protionamide
go.drugbank.com/drugs/DB12667ApprovedInvestigationalWithdrawnProthionamide has been used in trials studying the treatment of MDR-TB and HIV Infections.
Trenonacog alfa
go.drugbank.com/drugs/DB13201InvestigationalHuman coagulation factor IX (EC 3.4.21.22, Christmas factor, plasma thromboplastin component), produced in CHO cells.
Danofloxacin
go.drugbank.com/drugs/DB11393ExperimentalVet approvedDanofloxacin is an antibiotic agent from the family of the fluoroquinolones used in veterinary medicine.
Acetylcysteine zidrimer
go.drugbank.com/drugs/DB16496InvestigationalSynonyms: Dendrimer N-acetyl-cysteineOral Polio Vaccine
go.drugbank.com/drugs/DB15864InvestigationalAfter administration, OPV strains extensively multiply in the intestinal tract, becoming widely spread in the community to immunize a sizable proportion of those unvaccinated in the population[A220163] … The polio vaccine can be either administered in the inactivated form or the oral form, although both series comprises 4 doses and is also interchangeable in administration form so long all as 4 doses are