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Chloral hydrate
go.drugbank.com/drugs/DB01563ApprovedIllicitInvestigationalVet approvedIt is no longer considered useful as an anti-anxiety medication. … The safety margin is too narrow for chloral hydrate to be used as a general anesthetic in humans, but it is commonly used for that purpose in animal experiments.
Products: PMS-chloral Hydrate Syrup 100mg/ml, PMS-CHLORAL HYDRATE SYRUP 500 mg/5 mlBurosumab
go.drugbank.com/drugs/DB14012ApprovedInvestigationalIt causes impaired bone growth and development in children and adolescents and issues with bone mineralization throughout a patient’s life [L2346]. … Some adults with this condition suffer from persistent, unrelenting discomfort and complications, such as joint pain, impaired mobility, tooth abscesses and hearing loss [L2346].
Products: CRYSVITA ® SOLUCION PARA INYECCIÓN 10MG/MLCarbinoxamine
go.drugbank.com/drugs/DB00748ApprovedCarbinoxamine is a first generation antihistamine that competes with free histamine for binding at HA-receptor sites. … The product label for carbinoxamine as an over the counter cough and cold medicine is being modified to state "do not use" in children under 4 years of age in order to prevent and reduce misuse, as many
Mixtures: TEMPRA XT NOCHEProducts: Karbinal ER, CARBIMIN TABLETS 4MGSemaglutide
go.drugbank.com/drugs/DB13928ApprovedInvestigational[A186053] In June 2021, semaglutide was approved by the FDA for chronic weight management in adults with general obesity or overweight who have at least one weight-related condition, marking semaglutide … as the first approved drug for such use since 2014.
Products: Rybelsus 14mg Tablet, RYBELSUS® TABLET 14MGPentoxyverine
go.drugbank.com/drugs/DB11186ApprovedWithdrawnIt is an active ingredient in over-the-counter cough suppressants in combination with guaifenesin and H1-receptor antagonists [A32160]. … Pentoxyverine acts on sigma-1 receptors, as well as kappa and mu-opioid receptors. The FDA withdrew the use of all oral gel drug products containing pentoxyverine citrate.
Products: PENTOXYVERIN AL 19MG/MLNorfloxacin
go.drugbank.com/drugs/DB01059ApprovedInvestigationalA synthetic fluoroquinolone (fluoroquinolones) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA gyrase.
Products: PMS-norfloxacin, NORFLOXACINA EGSirolimus
go.drugbank.com/drugs/DB00877ApprovedInvestigational[A242412] It was first isolated and identified as an antifungal agent with potent anticandida activity; however, after its potent antitumor and immunosuppressive activities were later discovered, it was … it was shown to regulate longevity and maintain normal glucose homeostasis.
Products: RAPAMUNE TABLET 1MG, RAPAMUNE TABLETS (1MG)Nilvadipine
go.drugbank.com/drugs/DB06712ApprovedNilvadipine is a calcium channel blocker (CCB) for the treatment of hypertension.
Products: ESCOR FORTE 16MG RET KAP, ESCOR 8MG RETARDKAPSELNLetrozole
go.drugbank.com/drugs/DB01006ApprovedInvestigational[A190546] Letrozole was granted FDA approval on 25 July 1997.[L11623] … [A190543,A1559,L11623,L11626] It is a third generation aromatase inhibitor like [exemestane] and [anastrozole], meaning it does not significantly affect cortisol, aldosterone, and thyroxine.
Products: PMS-letrozole, LET®2.5MGHyperkeratosis follicularis et parafollicularis
go.drugbank.com/conditions/DBCOND0020027Drugs: Salicylic acidSynonyms: Hyperkeratosis follicularis et parafollicularis, Keratosis follicularis et parafollicularis in cutem penetrans