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Displaying results 561 - 570 of 10000 in total
  1. Target

    High affinity copper uptake protein 1

    go.drugbank.com/bio_entities/BE0003649
    TransporterHumans

    to copper(2+) reduction and probably followed by copper(1+) stabilization (PubMed:30489586). … :20451502, PubMed:20569931, PubMed:23658018) and delivers directly copper(1+) to specific chaperone such as ATOX1, via a copper(1+)- mediated transient interaction between the C-terminal domain and a copper

    Polypeptides: High affinity copper uptake protein 1Synonyms: Copper transporter 1
  2. Target

    Cytochrome b-c1 complex subunit 10

    go.drugbank.com/bio_entities/BE0003859
    TargetHumans

    The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase … Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.

    Polypeptides: Cytochrome b-c1 complex subunit 10Synonyms: Complex III subunit 10, Complex III subunit XI
  3. Target

    Cytochrome b-c1 complex subunit 7

    go.drugbank.com/bio_entities/BE0003860
    TargetHumans

    The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase … Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.

    Polypeptides: Cytochrome b-c1 complex subunit 7Synonyms: Complex III subunit 7, Complex III subunit VII
  4. Target

    Cytochrome b6-f complex subunit 6

    go.drugbank.com/bio_entities/BE0003907
    TargetMastigocladus laminosus

    PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex. … Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (PubMed:14526088

    Polypeptides: Cytochrome b6-f complex subunit 6Synonyms: Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI
  5. Target

    Trafficking protein particle complex subunit 6B

    go.drugbank.com/bio_entities/BE0004276
    TargetHumans

    Component of a transport protein particle (TRAPP) complex that may function in specific stages of inter-organelle traffic (PubMed:16025134, PubMed:16828797).

    Polypeptides: Trafficking protein particle complex subunit 6BSynonyms: TRAPP complex subunit 6B
  6. Target

    KAT8 regulatory NSL complex subunit 3

    go.drugbank.com/bio_entities/BE0009091
    TargetHumans

    Non-catalytic component of the NSL histone acetyltransferase complex, a multiprotein complex that mediates histone H4 acetylation at 'Lys-5'- and 'Lys-8' (H4K5ac and H4K8ac) at transcription start sites … The NSL complex also acts as a regulator of gene expression in mitochondria (PubMed:27768893).

    Polypeptides: KAT8 regulatory NSL complex subunit 3Synonyms: NSL complex protein NSL3
  7. Drug

    Mycophenolate mofetil

    go.drugbank.com/drugs/DB00688
    ApprovedInvestigational

    It demonstrates an increased bioavailability, a higher efficacy, and reduced gastrointestinal effects when compared to MPA.[A180826] … [L7363] It is marketed by Roche Pharmaceuticals and was granted FDA approval for the prophylaxis of transplant rejection in 1995.

    Synonyms: 2-morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoateProducts: Mycophenolatmofetil Accord 500 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung
  8. Indication

    Uncomplicated Urinary Tract Infections caused by Citrobacter freundii complex

    go.drugbank.com/conditions/DBCOND0173161
    Drugs: Gepotidacin
    Synonyms: Uncomplicated Urinary Tract Infections caused by Citrobacter freundii complex
  9. Drug

    Dasatinib

    go.drugbank.com/drugs/DB01254
    ApprovedInvestigational

    [A2226] The use of dasatinib was first approved by the FDA in 2006.[L45171,L45186] … [A2226,A11377] Also, mutations in the kinase domain of BCR-ABL may lead to relapse during imatinib treatment.

    Synonyms: N-(2-CHLORO-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamideProducts: DASATINIB EG
  10. Drug

    Itraconazole

    go.drugbank.com/drugs/DB01167
    ApprovedInvestigational

    [L50051] Itraconazole was first approved in the US in 1992 [L50056] and is available orally. … While the intravenous formulation of the drug was formerly available, it was discontinued in the US in 2007.[A263232]

    Products: ITRACONAZOLO EG