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CAR BCMA-CS1
go.drugbank.com/drugs/DB17313ExperimentalCAR BCMA-CS1 is a lentiviral transfected chimeric antigen receptor (CAR) T-cell therapy modified to target B-cell maturation antigen and CS1.
Synonyms: CAR BCMA-CS1, BCMA-CS1 cCAR T cell therapyTuberculin purified protein derivative
go.drugbank.com/drugs/DB11601ApprovedTuberculin Purified Protein Derivative (PPD) is a sterile aqueous solution of a purified protein fraction for intradermal administration as an aid in the diagnosis of tuberculosis. … The diagnostic test is commonly referred to as the Mantoux test which serves to minimize the risk of transmission of infection with *Mycobacterium tuberculosis* through early diagnosis and appropriate
Categories: Compounds used in a research, industrial, or household settingProducts: BIOCINE TESTPPD 5-UI/ 01 ML, PPD TÜBERKÜLİN 100 TU/2 ML İNTRADERMAL ENJEKSİYONLUK ÇÖZELTİ, 1 ADETDexpanthenol
go.drugbank.com/drugs/DB09357ApprovedInvestigationalDexpanthenol is enzymatically cleaved to form pantothenic acid, which is an essential component of Coenzyme A, which acts as a cofactor in many enzymatic reactions that are important for protein metabolism … Dexpanthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium.
Mixtures: Tini-cal Ampoules, K-FENIDEX JEL 30 GCategories: Vitamin B Complex, Vitamin D and AnaloguesBisoprolol
go.drugbank.com/drugs/DB00612ApprovedInvestigational[A180472,L7219] It is considered a potent drug with a long-half life that can be used once daily to reduce the need for multiple doses of antihypertensive drugs. … It may be used alone or in combination with other drugs to manage hypertension[L7219] and can be useful in patients with chronic obstructive pulmonary disease (COPD) due to its receptor selectivity.
Mixtures: ZIAC ® 5 MG, CORBIS® DCategories: P-glycoprotein inhibitors, P-glycoprotein substratesDarbepoetin alfa
go.drugbank.com/drugs/DB00012ApprovedInvestigationalHuman erythropoietin with 2 aa substitutions to enhance glycosylation (5 N-linked chains), 165 residues (MW=37 kD). Produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology.
Products: ARANESP® 10 UG SOLUCIÓN INYECTABLE EN JERINGA PRELLENADA, ARANESP® 300 UG SOLUCIÓN INYECTABLE EN JERINGA PRELLENADAChimeric antigen receptor T-cells
go.drugbank.com/drugs/DB22146InvestigationalChimeric Antigen Receptor T-cells is under investigation in clinical trial NCT05225363 (Modified Immune Cells (TAG72-CAR T Cells) for the Treatment of Patients With Platinum Resistant Epithelial Ovarian
Synonyms: CAR T, CAR - TRecombinant Bacterial ACE2 Receptors-like Enzyme
go.drugbank.com/drugs/DB15741InvestigationalB38-CAP is structured as a carboxypeptidase and derived from _Paenibacillus sp._ The molecule, an Angiotensin Converting Enzyme 2 (ACE2)-like enzyme, shares structural similarities to the mammalian ACE2 … B38-CAP is an ACE2-like enzyme which decreases angiotensin II levels. It is being investigated for treating hypertension, myocardial fibrosis, and cardiac dysfunction.
Synonyms: B38-CAPAllogeneic Cardiosphere-Derived Cells
go.drugbank.com/drugs/DB15744InvestigationalThey exert their effects by secreting exosomes: nanometer-sized, membrane-bound vesicles used for the purpose of cell-cell communication. … TNFa, IFN-y, IL-1B, and IL-15). The anti-inflammatory effects of CDC work through polarizing macrophages and restoring tissue function.
Synonyms: CAP-1002A, CAP-1002BHepatitis B immune globulin
go.drugbank.com/drugs/DB05276ApprovedInvestigationalLong-term hepatitis B immune globulin (HBIG) has been shown to reduce hepatitis B virus (HBV) reinfection in patients transplanted for hepatitis B. … Infection with hepatitis B may lead to hepatocellular carcinoma, a type of liver cancer. Therefore, the hepatitis-B vaccines are cancer-preventing vaccines.
Categories: hepatitis B immunoglobulinSynonyms: Hepatitis B immune globulin, Hepatitis B immune globulin humanTorasemide
go.drugbank.com/drugs/DB00214ApprovedInvestigational[A319] Torasemide was first approved for clinical use by the FDA in 1993.[L5257] … Torasemide is a high-ceiling loop diuretic.[A174463] Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent.
Synonyms: N-(((1-Methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-3-pyridinesulfonamide, 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)ureaCategories: Non Potassium Sparing Diuretics, Cytochrome P-450 Substrates