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Displaying results 5691 - 5700 of 10000 in total
  1. Drug

    Sevabertinib

    go.drugbank.com/drugs/DB21667
    ApprovedInvestigational

    [L64186] Sevabertinib functions as a reversible kinase inhibitor of human epidermal growth factor receptor 2 (HER2), also exhibiting activity against epidermal growth factor receptor (EGFR). … Sevabertinib is a kinase inhibitor indicated for adult patients with locally advanced or metastatic non-squamous non-small cell lung cancer (NSCLC) whose tumors have HER2 (ERBB2) tyrosine kinase domain

    Categories: MATE 2-K Inhibitors, MATE 1 Inhibitors
  2. Drug

    Gadoquatrane

    go.drugbank.com/drugs/DB33282
    Approved

    Gadoquatrane is a macrocyclic gadolinium-based contrast agent used to enhance magnetic resonance imaging. … to use the lowest gadolinium dose sufficient to image a patient.

  3. Drug

    Potrasertib

    go.drugbank.com/drugs/DB21682
    Experimental

    Potrasertib is a small molecule drug. The usage of the INN stem '-sertib' in the name indicates that Potrasertib is a serine/threonine kinase inhibitor. … Potrasertib has a monoisotopic molecular weight of 564.19 Da.

  4. Drug

    Frespaciguat

    go.drugbank.com/drugs/DB21683
    Investigational

    Frespaciguat is a small molecule drug. The usage of the INN stem '-ciguat' in the name indicates that Frespaciguat is a guanylate cyclase activator and stimulator. … Frespaciguat has a monoisotopic molecular weight of 608.14 Da.

  5. Drug

    Padoprazan

    go.drugbank.com/drugs/DB21689
    Experimental

    Padoprazan is a small molecule drug. The usage of the INN stem '-prazan' in the name indicates that Padoprazan is a proton pump inhibitor, not dependent on acid activation. … Padoprazan has a monoisotopic molecular weight of 405.12 Da.

  6. Drug

    Laroprovstat

    go.drugbank.com/drugs/DB21690
    Investigational

    Laroprovstat is a small molecule drug. Laroprovstat has a monoisotopic molecular weight of 414.16 Da.

  7. Drug

    Evategrel

    go.drugbank.com/drugs/DB21691
    Experimental

    Evategrel is a small molecule drug. Evategrel has a monoisotopic molecular weight of 471.11 Da.

  8. Drug

    Vicadrostat

    go.drugbank.com/drugs/DB21693
    Investigational

    Vicadrostat is a small molecule drug. The usage of the INN stem '-drostat' in the name indicates that Vicadrostat is a inhibitor of the synthesis of aldosterone and cortisol. … Vicadrostat is under investigation in clinical trial NCT07064473 (A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular

  9. Drug

    Luvometinib

    go.drugbank.com/drugs/DB21696
    Investigational

    Luvometinib is a small molecule drug. The usage of the INN stem '-tinib' in the name indicates that Luvometinib is a tyrosine kinase inhibitor. … Luvometinib has a monoisotopic molecular weight of 665.04 Da.

  10. Drug

    Tigemocoxib

    go.drugbank.com/drugs/DB21699
    Experimental

    Tigemocoxib is a small molecule drug. The usage of the INN stem '-coxib' in the name indicates that Tigemocoxib is a selective cyclo-oxygenase inhibitor. … Tigemocoxib has a monoisotopic molecular weight of 334.06 Da.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring