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Displaying results 5711 - 5720 of 10000 in total
  1. Drug

    Ambroxol

    go.drugbank.com/drugs/DB06742
    ApprovedInvestigational

    The substance is a mucoactive drug with several properties including secretolytic and secretomotoric actions that restore the physiological clearance mechanisms of the respiratory tract which play an important … Ambroxol is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Lasolvan or Mucoangin.

    Mixtures: MATIS-A, TOS-XOL ® JARABECategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  2. Drug

    Bivalirudin

    go.drugbank.com/drugs/DB00006
    ApprovedInvestigational

    Bivalirudin is a synthetic 20 residue peptide (thrombin inhibitor) which reversibly inhibits thrombin.

    Products: ANGIOMAX® POLVO LIOFILIZADO PARA RECONSTRUIR A SOLUCIÓN INYECTABLE (50MG/ML), BIVACARD 250 MG IV ENJEKSIYON VE INFÜZYON IÇIN LIYOFILIZE TOZ IÇEREN FLAKON, 1 ADET
  3. Drug

    Fish oil

    go.drugbank.com/drugs/DB13961
    ApprovedInvestigationalNutraceutical

    Fish oil is a component of SMOFLIPID, which was FDA approved in July 2016. … demonstrated abilities in minimizing or preventing hypertriglyceridemia when taken as an adjunct to a healthy diet [FDA Label].

    Mixtures: VINATAL DHA CAPSULA DE GELATINA BLANDA, SmofKabiven Low Osmo peripher Emulsion zur InfusionCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  4. Drug

    Bisoprolol

    go.drugbank.com/drugs/DB00612
    ApprovedInvestigational

    [A180472,L7219] It is considered a potent drug with a long-half life that can be used once daily to reduce the need for multiple doses of antihypertensive drugs. … [A180472] Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor selectivity and is a useful alternative to non-selective β-blocker drugs in the treatment of hypertension such

    Mixtures: CORBIS® D, BISOPLUS AL 5/12.5MGCategories: P-glycoprotein inhibitors, P-glycoprotein substrates
  5. Drug

    Ampicillin

    go.drugbank.com/drugs/DB00415
    ApprovedInvestigationalVet approved

    Ampicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.

    Mixtures: AUROPENNZ 1.5 G POLVO ESTERIL PARA RECONSTITUIR A SOLUCION INYECTABLE, AMPICILLINA E SULBACTAM IBICategories: Penicillin G, Heterocyclic Compounds, 2-Ring
  6. Indication

    Conditions where a reduction of gastric acid secretion is required

    go.drugbank.com/conditions/DBCOND0117234
    Drugs: Pantoprazole
    Synonyms: Conditions where a reduction of gastric acid secretion is required
  7. Drug

    Tigecycline

    go.drugbank.com/drugs/DB00560
    ApprovedInvestigational

    Tigecycline is a glycylcycline antibiotic developed and marketed by Wyeth under the brand name Tygacil. … It was developed in response to the growing prevalence of antibiotic resistance in bacteria such as Staphylococcus aureus. It was granted fast-track approval by the U.S.

    Synonyms: (4S,4aS,5aR,12aS)-9-(2-(tert-butylamino)acetamido)-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamideProducts: TIGECLIN ® POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE., TIGEVITAE® 50 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE
  8. Target

    Pleckstrin homology domain-containing family A member 4

    go.drugbank.com/bio_entities/BE0001278
    TargetHumans

    Binds specifically to phosphatidylinositol 3-phosphate (PtdIns3P), but not to other phosphoinositides

    Polypeptides: Pleckstrin homology domain-containing family A member 4Synonyms: PH domain-containing family A member 4
  9. Target

    Pleckstrin homology domain-containing family A member 1

    go.drugbank.com/bio_entities/BE0003262
    TargetHumans

    Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane

    Polypeptides: Pleckstrin homology domain-containing family A member 1Synonyms: PH domain-containing family A member 1
  10. Target

    Potassium voltage-gated channel subfamily A member 4

    go.drugbank.com/bio_entities/BE0004502
    TargetHumans

    Likewise, a heterotetrameric channel formed by KCNA1 and KCNA4 shows rapid inactivation (PubMed:17156368) … Homotetrameric KCNA4 forms a potassium channel that opens in response to membrane depolarization, followed by rapid spontaneous channel closure (PubMed:19912772, PubMed:8495559).

    Polypeptides: Potassium voltage-gated channel subfamily A member 4