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Displaying results 5711 - 5720 of 10000 in total
  1. Drug

    Alefacept

    go.drugbank.com/drugs/DB00092
    ApprovedWithdrawn

    Immunosuppressive dimeric fusion protein that consists of the extracellular CD2-binding portion of the human leukocyte function antigen-3 (LFA-3) linked to the Fc (hinge, CH2 and CH3 domains) portion of

    Categories: CD2-directed LFA-3/Fc Fusion Protein
  2. Drug

    Coagulation Factor IX (Recombinant)

    go.drugbank.com/drugs/DB00100
    Approved

    medium that is then processed and purified for use as a pharmaceutical agent. … Recombinant Coagulation Factor IX is a purified Factor IX glycoprotein produced by recombinant DNA technology.

    Products: OCTANINE® F 500 UI, OCTANINE F ® 250 UI
  3. Drug

    Agalsidase beta

    go.drugbank.com/drugs/DB00103
    ApprovedInvestigational

    Agalsidase beta is a recombinant human α-galactosidase A similar to [agalsidase alfa]. … [A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa, after a contamination event in 2009.

    Products: ฟาบราไซม์ (5 มก.), REPLAGAL 1 MG/ML IV İNFÜZYONLUK KONSANTRE ÇÖZELTİ, 1 ADET
  4. Drug

    Bevacizumab

    go.drugbank.com/drugs/DB00112
    ApprovedInvestigational

    [A192834,A192888,A192837,A192891,A192894] Bevacizumab is a humanized monoclonal IgG antibody that inhibits angiogenesis by binding and neutralizing VEGF-A. … There is a great deal of evidence indicating that vascular endothelial growth factor (VEGF) is important for the survival and proliferation of cancer cells.

    Categories: VEGF/VEGFR (Vascular Endothelial Growth Factor / -Receptor) inhibitorsSynonyms: 贝伐珠单抗
  5. Drug

    Technetium Tc-99m arcitumomab

    go.drugbank.com/drugs/DB00113
    Experimental

    The molecule has a molecular weight of ~54,000 Daltons. … Reduced Fab fragment of the murine IgG1 monoclonal antibody IMMU-4 (also called NP-4) with specificity for carcinoembryonic antigen (CEA) covalently labeled with Technitium 99.

  6. Drug

    Acarbose

    go.drugbank.com/drugs/DB00284
    ApprovedInvestigational

    Acarbose is a complex oligosaccharide that acts as an inhibitor of several enzymes responsible for the breakdown of complex carbohydrates in the intestines. … Acarbose is therefore used in conjunction with diet, exercise, and other pharmacotherapies for the management of blood sugar levels in patients with type 2 diabetes.

    Products: GLUCOBAY® 50MG TABLETAS, GLUCOBAY® 100MG TABLETAS
  7. Drug

    Bleomycin

    go.drugbank.com/drugs/DB00290
    ApprovedInvestigational

    A complex of related glycopeptide antibiotics from <i>Streptomyces verticillus</i> consisting of bleomycin A2 and B2 (B2 CAS # 9060-10-0).

    Products: BLOMINDEX® POLVO LIOFILIZADO PARA INYECCION 15 U, ONCOBLEOCIN®
  8. Drug

    Capreomycin

    go.drugbank.com/drugs/DB00314
    ApprovedInvestigational

    Cyclic peptide antibiotic similar to viomycin. It is produced by Streptomyces capreolus.

    Categories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index
  9. Drug

    Icodextrin

    go.drugbank.com/drugs/DB00702
    ApprovedInvestigational

    It is injected as a solution into the peritoneal cavity. The drug is absorbed via convective transport via peritoneal lymphatic pathways.

    Mixtures: EXTRANEAL PERITONEAL DIALYSIS SOLUTION 75 g/l, EXTRANEAL PERITONEAL DIALYSIS SOLUTION 75G/LCategories: Compounds used in a research, industrial, or household setting
  10. Drug

    Eculizumab

    go.drugbank.com/drugs/DB01257
    ApprovedInvestigational

    [L6919,A2245] Binding to this protein prevents the activation of a complement terminal complex, which is used to treat a number of autoimmune conditions. … Eculizumab is a monoclonal antibody that targets complement protein C5.

    Products: SOLIRIS ® 300 MGSOLUCION PARA INFUSIÓN INTRAVENOSA, ELIZARIA® 10MG/ML SOLUCIÓN CONCENTRADA PARA INFUSIÓN