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Displaying results 5721 - 5730 of 10000 in total
  1. Drug

    Libivirumab

    go.drugbank.com/drugs/DB17748
    Experimental

    It is one of the active ingredients in HepeX-B, a drug product containing two human monoclonal antibodies to the hepatitis B virus (HBV) surface antigen.[A259202] … Libivirumab is an investigational monoclonal antibody.

    Synonyms: Immunoglobulin g, anti-(hepatitis b surface antigen) (human monoclonal 17.1.41 heavy chain), disulfide with human monoclonal 17.1.41 .kappa.-chain, dimer
  2. Drug

    Ketazocine

    go.drugbank.com/drugs/DB20132
    Experimental

    Ketazocine is a small molecule drug. The usage of the INN stem '-azocine' in the name indicates that Ketazocine is a narcotic antagonist/agonist related to 6,7-benzomorphan. … Ketazocine has a monoisotopic molecular weight of 285.17 Da.

    Categories: Heterocyclic Compounds, 1-Ring
  3. Drug

    T487

    go.drugbank.com/drugs/DB05474
    Experimental

    T487 is a small molecule chemokine receptor antagonist to correct or modify immune system responses. It binds selectively and potently to CXCR3. … The formulation is administered orally and has anti-inflammatory effects in conditions such as rheumatoid arthritis, inflammatory bowel disease and psoriasis.

  4. Drug

    RPI-78M

    go.drugbank.com/drugs/DB05740
    Experimental

    RPI-78M is being developed for the treatment of multiple sclerosis (MS). … Other neurological disorders that may be served by RPI-78M include myasthenia gravis (MG), muscular dystrophy (MD) and amyotrophic lateral sclerosis (ALS).

  5. Drug

    Antipain

    go.drugbank.com/drugs/DB15251
    Experimental

    [A214484, A214487] Antipain was used in 2010 to obtain a crystal structure of the _Leishmania major_ oligopeptidase B (OPB), a serine protease that serves as a virulence factor in trypanosomatids. … [A214481] Early studies investigated the potential for antipain to alter DNA damage and chromosomal aberrations in irradiated cells or those treated with chemical mutagens such as _N_-methyl-_N_'-nitro

  6. Drug

    Covax-19™

    go.drugbank.com/drugs/DB15846
    Investigational

    As of June 2020, the vaccine is in Phase 1 trials to evaluate safety and immune responses (NCT04428073). … Phase 2 and 3 trials are planned for September 2020, and the vaccine is expected to launch early in 2021.

  7. Drug

    Epitestosterone

    go.drugbank.com/drugs/DB07768
    Experimental

    Epitestosterone is the 17-alpha isomer of testosterone, derived from pregnenolone via the delta5-steroid pathway, and via 5-androstene-3-beta,17-alpha-diol. … Epitestosterone acts as an antiandrogen in various target tissues. The ratio between testosterone/epitestosterone is used to monitor anabolic drug abuse.

    Synonyms: 17-alpha-Hydroxyandrost-4-en-3-one, (17-alpha)-17-Hydroxyandrost-4-en-3-one
  8. Drug

    Mannose 6-phosphate

    go.drugbank.com/drugs/DB11848
    Investigational

    Mannose 6-phosphate has been used in trials studying the treatment of Wound, Cicatrix, Wound-healing, and Re-epithelialisation.

    Synonyms: Mannose 6-phosphate
  9. Drug

    JTK-853

    go.drugbank.com/drugs/DB13095
    Investigational

    JTK-853 has been used in trials studying the treatment of Hepatitis C Virus Infection, Response to Therapy of.

    Categories: Heterocyclic Compounds, 1-Ring
  10. Drug

    Chlorphenesin

    go.drugbank.com/drugs/DB00856
    Approved

    Synonyms: 3-(4-chlorophenoxy)-1,2-propanediol, 3-(p-chlorophenoxy)-1,2-propanediolMixtures: Medi SM 24K Gold Hydrogel Peptide Mask Pack