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Zeteletinib
go.drugbank.com/drugs/DB21491InvestigationalZeteletinib is under investigation in clinical trial NCT03780517 (Safety, Efficacy, and Tolerability of BOS172738 in Patients With Advanced Rearranged During Transfection (RET) Gene-Altered Tumors).
Synonyms: Ret inhibitor ds-5010Enlonstobart
go.drugbank.com/drugs/DB21890Investigational[A274486] It targets the programmed cell death protein 1 (PD-1), is being developed by the CSPC Pharmaceutical Group for the treatment of advanced cervical cancer and other solid tumours.
Mitoquinone
go.drugbank.com/drugs/DB05063InvestigationalMitoquinone is based on a novel technology, targeted lipophilic cations, that transport and concentrate antioxidants into the mitochondria -- organelles inside cells that provide energy for life processes -- where they accumulate up to a...
IDM-4
go.drugbank.com/drugs/DB05438ExperimentalIt is a monoclonal antibody-specific antigen that can selectively target cancer-affected cells by coupling with tumor cell-killing MAK cells, which are derived from the patient's own monocytes.
N,N,N-trimethylglycinium
go.drugbank.com/drugs/DB04455Investigational(From Martindale, The Extra Pharmacopoeia, 30th ed, p1341)
ILY101
go.drugbank.com/drugs/DB05059InvestigationalILY101 is a metal-free, non-absorbed polymeric drug designed for the selective binding and removal of phosphate anions from the gastrointestinal tract. ILY101 is being developed for the treatment of hyperphosphatemia in CKD patients on d...
Thymoquinone
go.drugbank.com/drugs/DB16447InvestigationalThymoquinone is a natural compound with widespread protective effects, including anti-oxidative, anti-inflammatory, immunomodulatory, anti-cancer, and anti-microbial.
Tetrathiomolybdate
go.drugbank.com/drugs/DB05088InvestigationalIt is also developed for fibrotic disorders based upon the rationale that the fibrotic disease process is dependent upon the availability of free copper in the body.