Ocaperidone

DB06229ExperimentalSmall molecule

Investigated for use/treatment in schizophrenia and schizoaffective disorders.

Mechanism: Ocaperidone is a benzisoxazol piperidine antipsychotic primarily binds and with high affinity to 5-HT2 (serotonin) receptors, alpha1 and alpha 2 adrenergic receptors, dopamine D2 receptors and histamine H1 receptors. Ocaperidone is an antagonist primarily at the 5HT and D2 receptors. A proposed mechanism of action is the central D2 receptor blockade which is common to all neuroleptics that are used to treat positive symptoms of schizophrenia.
Curator reviewed
Primary indication: Investigated for use/treatment in schizophrenia and schizoaffective disorders.Curator reviewed
Formula / weight: C₂₄H₂₅FN₄O₂ · 420.488 g/mol (avg)
Code names: ND-1087 · R-79598

Resolves to

Compound

Structure

InChIKeyZZQNEJILGNNOEP-UHFFFAOYSA-NSMILESCC1=CC=CN2C(=O)C(CCN3CCC(CC3)C3=NOC4=CC(F)=CC=C34)=C(C)N=C12

Targets

What you can answer from here — as of March 06, 2025

11Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

10+ReferencesStructured and connected to the statements they support

Which drugs share a target with Ocaperidone, and which of those have an active Phase 3 trial?

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