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Choline C 11
go.drugbank.com/drugs/DB09277ApprovedCholine C 11 is a marker for cellular proliferation as its main molecule is a precursor for the biosynthesis of phospholipids which are essential components of all cell membranes.
Synonyms: Choline C 11N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl)-L-prolinamide
go.drugbank.com/drugs/DB06942ExperimentalN-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl)-l-prolinamide is a solid. This compound belongs to the alpha amino acid amides. These are amide derivatives of alpha amino acids. … This medication targets the protein prothrombin.
Synonyms: N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl)-L-prolinamideTrenbolone
go.drugbank.com/drugs/DB11551ExperimentalVet approvedTrenbolone, also known as trienolone or trienbolone, is a steroid used on livestock to increase muscle growth and appetite. … To increase its effective half-life, trenbolone is administered as a prodrug as an ester conjugate such as [trenbolone acetate], trenbolone enanthate, or trenbolone cyclohexylmethylcarbonate.
Synonyms: 17-b-Hydroxyestra-4,9,11-trien-3-one, 17-β-hydroxyestra-4,9,11-trien-3-oneCyclic GMP
go.drugbank.com/drugs/DB02315ExperimentalCyclic guanosine monophosphate (Cyclic GMP) is a guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. … Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. (From Merck Index, 11th ed)
Synonyms: 3',5'-cyclic GMP, Guanosine 3',5'-cyclic phosphateCategories: Heterocyclic Compounds, 2-RingXL844
go.drugbank.com/drugs/DB05149InvestigationalXL844 is investigated for the use and treatment solid tumors. XL844 is a solid. … XL844 is a potent inhibitor of the checkpoint kinases CHK1 and CHK2, which induce cell cycle arrest in response to a variety of DNA damaging agents.
Tunicamycin
go.drugbank.com/drugs/DB13172ExperimentalOne member of this family is the enzyme GlcNAc phosphotransferase (GPT), which catalyzes the transfer of N-acetylglucosamine-1-phosphate from UDP-N-acetylglucosamine to dolichol phosphate in the first … Tunicamycin blocks N-linked glycosylation (N-glycans) resulting in cell cycle arrest at the G1 phase in human cells. It is used as an experimental tool to induce unfolded protein response.
Categories: Heterocyclic Compounds, 1-RingDeracoxib
go.drugbank.com/drugs/DB11395ExperimentalVet approvedDeracoxib is a non-steroidal anti-inflammatory drug of the coxib class, used in veterinary medicine to treat osteoarthritis in dogs. … It is sold in tablets, which have added beefy flavour to increase palatability.
Categories: Heterocyclic Compounds, 1-RingV591
go.drugbank.com/drugs/DB16438InvestigationalThe V591 vaccine, part of Merck’s COVID-19 vaccine programming, was developed using a modified measles vaccine virus as a vector for COVID-19 antigen delivery[L30593]. … Through Merck’s acquisition of Thermis in May 2020, they were able to leverage Thermis’ platform knowledge and accelerate the development of V591 to phase I clinical trials (NCT04498247)[L30593].
MLN-977
go.drugbank.com/drugs/DB05431ExperimentalMLN-977 is a small molecule compound that inhibits the production of leukotrienes, especially 5-lipoxygenase. It is developed by PharmaEngine to treat asthma and chronic obstructive pulmonary disease.
Probiorinse
go.drugbank.com/drugs/DB15870Experimental[L16368] This strain of bacteria is said to have salubrious effects on the microbiome of the nasal cavity and sinuses.[A220193] … Probiorinse is an intranasal probiotic treatment composed of a pre-mixed and buffered sinus irrigation solution that contains the probiotic bacteria Lactococcus lactis W136.