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Acetazolamide
go.drugbank.com/drugs/DB00819ApprovedInvestigationalVet approvedIt is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual … Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition
Synonyms: N-[5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl]acetamide, N-[5-(aminosulfonyl)-1,3,5-thiadiazol-2-yl]acetamideProducts: VICLEAR(R), Diamox IV 500mgBismuth subsalicylate
go.drugbank.com/drugs/DB01294ApprovedVet approved[A230733] Bismuth subsalicylate has been around for over 100 years: it was originally developed in 1901 for hygienic use and sanitation for cholera infection. … Exhibiting antibacterial and gastroprotective properties, bismuth subsalicylate is an insoluble salt of [salicylic acid] linked to trivalent [bismuth cation].
Mixtures: Pepto-Bismol and Pepto-Bismol To Go, Pepto-Bismol and Pepto-Bismol To GoProducts: Rx Act Stomach Relief, PEPTIMAX FSRCefoxitin
go.drugbank.com/drugs/DB01331ApprovedInvestigationalCefoxitin is a semi-synthetic, broad-spectrum cepha antibiotic for intravenous administration. It is derived from cephamycin C, which is produced by <i>Streptomyces lactamdurans</i>.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: Cefoxitin for Injection, Cefoxitin for Injection USPNeostigmine
go.drugbank.com/drugs/DB01400ApprovedInvestigationalVet approvedA cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. … Neostigmine, unlike physostigmine, does not cross the blood-brain barrier.
Synonyms: 3-Trimethylammoniumphenyl N,N-dimethylcarbamateProducts: NEOSTIGMIN 0,5 MG/ML IM/IV/SC ENJEKSİYONLUK ÇÖZELTİ, , 6 ADET, NEOSTİGMİN 0,5 MG/ML IM/IV/SC ENJEKSİYONLUK ÇÖZELTİ, , 50 ADETEdaravone
go.drugbank.com/drugs/DB12243ApprovedInvestigationalHowever, the drug manufacturer, Mitsubishi Tanabe Pharma, withdrew the Marketing Authorization Application (MAA) for edaravone from the European market on May 24, 2019, in response to the request made … [L44007] It was later approved for the treatment of amyotrophic lateral sclerosis (ALS) in Japan and South Korea in 2015, followed by the FDA approval in May 2017 [L41810] and Health Canada approval in
Categories: Compounds used in a research, industrial, or household settingProducts: RADICAVA™ IV Concentrate Solution for Infusion 30mg/20mLPalivizumab
go.drugbank.com/drugs/DB00110ApprovedInvestigationalHumanized monoclonal antibody (IgG1k) produced by recombinant DNA technology, directed to an epitope in the A antigenic site of the F protein of respiratory syncytial virus (RSV). … Palivizumab is composed of to heavy chains (50.6 kDa each) and two light chains (27.6 kDa each), contains 1-2% carbohydrate by weight and has a molecular weight of 147.7 kDa +/- 1 kDa (MALDI-TOF)
Categories: Antiinfectives for Systemic UseProducts: Synagis 100mg/ml solution for Injection, SYNAGIS SOLUTION FOR INJECTION 100MG/MLObinutuzumab
go.drugbank.com/drugs/DB08935ApprovedInvestigationalThis chemical modification significantly enhances its affinity for FcγRIII receptors on immune effector cells. … [L54521] Like other drugs in its class, obinutuzumab targets the CD20 antigen expressed on the surface of pre-B and mature B lymphocytes, mediating B-cell lysis.
Products: GAZYVA 1000 MG/ 40 ML CONCENTRATE FOR SOLUTION FOR INFUSION, GAZYVA CONCENTRATE FOR SOLUTION FOR INFUSION 1000MG/40MLMometasone
go.drugbank.com/drugs/DB00764ApprovedInvestigationalMometasone is a corticosteroid not currently used in medical products. [Mometasone furoate] however, is still in use.
Categories: Corticosteroids for inhalation use, Drugs for Obstructive Airway DiseasesProducts: MONOVO 1MG/G SALBE, MOMECUTAN SALBE 1 MG/GTerlipressin
go.drugbank.com/drugs/DB02638ApprovedInvestigationalCompared to endogenous vasopressin, terlipressin has a longer half life and increased selectivity for the V1 receptor. … Terlipressin is a synthetic analogue of vasopressin, which is an endogenous neurohormone that acts as a vasoconstrictor.[A2601] It is a prodrug of [lypressin], or lysine vasopressin.
Products: GLYPRESSIN FOR INJECTION 1 mg/vial, GLYPRESSIN 1mg/8.5ml solution for injectionPentamidine
go.drugbank.com/drugs/DB00738ApprovedInvestigationalAntiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of pneumocystis pneumonia in HIV-infected patients. … It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
Categories: Antibiotics for Pneumocystis PneumoniaProducts: Pentamidine Isetionate for Injection BP, DBL PENTAMIDINE ISETHIONATE FOR INJECTION BP 300 mg/vial