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Perphenazine
go.drugbank.com/drugs/DB00850ApprovedInvestigationalAn antipsychotic phenothiazine derivative with actions and uses similar to those of chlorpromazine.
Mixtures: Perphenazine and Amitriptyline Hydrochloride, Perphenazine and Amitriptyline HydrochlorideProducts: Trilafon Conc 16mg/5ml, PMS Perphenazine Tab 16mgTramadol
go.drugbank.com/drugs/DB00193ApprovedInvestigationalTramadol differs from other traditional opioid medications in that it doesn't just act as a μ-opioid agonist, but also affects monoamines by modulating the effects of neurotransmitters involved in the … These pathways are complementary and synergistic, improving tramadol's ability to modulate the perception of and response to pain.
Mixtures: DICLOFENACO SODICO /TRAMADOL HCL 25 MG/25MG., Trabest 37.5mg/325mg TabletsCategories: tramadol and celecoxib, tramadol and paracetamolMethyl salicylate
go.drugbank.com/drugs/DB09543ApprovedInvestigationalVet approvedMethyl salicylate (oil of wintergreen or wintergreen oil) is an organic ester naturally produced by many species of plants, particularly wintergreens. … It forms a colorless to yellow or reddish liquid and exhibits a characteristic odor and taste of wintergreen.
Mixtures: Walgreens Cool n Heat Muscle and Joint Pain Relief Extra Strength, DFS 75mg DR/MS 25%/MENTH 6%/CAP 0.025% PAKSynonyms: Methyl o-hydroxybenzoateValsartan
go.drugbank.com/drugs/DB00177ApprovedInvestigationalARBs have been shown to have a protective effect on the heart by improving cardiac function, reducing afterload, increasing cardiac output and preventing ventricular hypertrophy and remodelling. … [A174154] By comparison, the angiotensin-converting enzyme inhibitor (ACEI) class of medications (which includes drugs such as [ramipril], [lisinopril], and [perindopril]) inhibit the conversion of
Mixtures: CO DIOVAN FORTE 160MG/25MG, Exforge HCT Tablet 10mg/160mg/25mgCategories: Agents Acting on the Renin-Angiotensin System, valsartan and nebivololCalcium polycarbophil
go.drugbank.com/drugs/DB14684ApprovedLess gas and bloating compared to psyllium laxative products, but can cause heartburn, and belly cramps. It is insoluble in water, dilute acids, and dilute alkali. … is physiologically inert, and does not cause gastrointestinal irritation.
Categories: Alimentary Tract and MetabolismProducts: Up and Up Fiber Therapy, Foster and Thrive Fiber Laxative 147Pasireotide
go.drugbank.com/drugs/DB06663ApprovedInvestigationalPasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease.
Synonyms: cyclo((4R)-4-(2-aminoethylcarbamoyloxy)-L-prolyl-L-phenylglycyl-D-tryptophyl-L-lysyl-4-O-benzyl-L-tyrosyl-L- phenylalanyl-)Categories: Pituitary and Hypothalamic Hormones and Analogues, Sex Hormones and InsulinsManidipine
go.drugbank.com/drugs/DB09238ApprovedInvestigationalWithdrawnIt is selective for vasculature and does not produce effects on the heart at clinically relevant dosages. … Manidipine (INN) is a calcium channel blocker (dihydropyridine type) that is used clinically as an antihypertensive.
Mixtures: VIVACE 30/10MG TABLETTEN, VIVACE 30/10MG TABLETTENCategories: delapril and manidipine, ACE Inhibitors and Calcium Channel BlockersMidazolam
go.drugbank.com/drugs/DB00683ApprovedIllicitInvestigationaland endoscopic procedures as pre-anesthetic medication, and as an adjunct to local anesthesia. … [F2977] This drug was initially approved by the US FDA in 1985, and has been approved for various indications since.
Categories: Hypnotics and Sedatives, Benzodiazepine hypnotics and sedativesProducts: N/a, MIDAZOLAM 50MG/10MLButorphanol
go.drugbank.com/drugs/DB00611ApprovedIllicitVet approvedA synthetic morphinan analgesic with narcotic antagonist action. It is used in the management of severe pain.
Synonyms: (−)-N-cyclobutylmethyl-3,14-dihydroxymorphinanCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeIntracellular Signalling Through PGD2 receptor and Prostaglandin D2
smpdb.ca/view/SMP0000343SignalingPGD is the major prostanoid released from human mast cells upon immunological challenge. Prostaglandin D2 (PGD2) can trigger asthmatic responses by acting as a cell-derived mediator in mice. The PGD receptor activates G(s) proteins which...