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Displaying results 571 - 580 of 5920 in total
  1. Drug

    Repaglinide

    go.drugbank.com/drugs/DB00912
    ApprovedInvestigational

    Repaglinide metabolites do not possess appreciable hypoglycemic activity. Approximately 90% of a single orally administered dose is eliminated in feces and 8% in urine. … Due to their mechanism of action, meglitinides may cause hypoglycemia although the risk is thought to be lower than that of sulfonylureas since their action is dependent on the presence of glucose.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: REPAGLINIDE DR. REDDY'S
  2. Drug

    Glucosamine

    go.drugbank.com/drugs/DB01296
    Approved

    Glucosamine is commonly used over the counter as a treatment for arthritic joint pain, although its acceptance as a medical therapy varies due to contradictory and findings with unclear clinical significance

    Mixtures: GLUCONITRIN D, GLUCONITRIN DSynonyms: D-Glucosamine, 2-amino-2-deoxy-D-glucose
  3. Drug

    Sodium hydroxide

    go.drugbank.com/drugs/DB11151
    Approved

    According to the the FDA, sodium hydroxide is considered a direct food recognized as safe, where it serves as a pH control agent and follows good manufacturing guidelines [L1967].

  4. Drug

    Pipemidic acid

    go.drugbank.com/drugs/DB13823
    Investigational

    Pipemidic acid is a quinolone antibacterial agent with activity against various gram-positive and gram-negative bacteria.

    Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme InhibitorsProducts: ACIDO PIPEMIDICO DR. REDDY'S
  5. Drug

    Nimesulide

    go.drugbank.com/drugs/DB04743
    ApprovedWithdrawn

    Due to concerns about the risk of hepatotoxicity, nimesulide has been withdrawn from market in many countries.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: NIMESULIDE DR. REDDY'S
  6. Drug

    Ramipril

    go.drugbank.com/drugs/DB00178
    ApprovedInvestigational

    Ramipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. Ramiprilat is a potent, competitive inhibitor of AC...

    Mixtures: DELIX DUO 2.5 MG/2.5 MG TABLET, 30 ADET, DELIX DUO 5 MG/5 MG FİLM KAPLI TABLET, 30 ADETProducts: RAMIPRIL DR. REDDY'S
  7. Drug

    Formoterol

    go.drugbank.com/drugs/DB00983
    ApprovedInvestigational

    Formoterol is an inhaled beta2-agonist used in the management of COPD and asthma that was first approved for use in the United States in 2001. It acts on bronchial smooth muscle to dilate and relax airways, and is administered as a racem...

    Mixtures: SYMBICORT PI 80/4.5UG120ED, SYMBICORT PI 80/4.5UG120EDCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 Substrates
  8. Drug

    Bupropion

    go.drugbank.com/drugs/DB01156
    ApprovedInvestigational

    Bupropion (also known as the brand name product Wellbutrin®) is a norepinephrine/dopamine-reuptake inhibitor (NDRI) used most commonly for the management of Major Depressive Disorder (MDD), Seasonal Affective Disorder (SAD), and as an ai...

    Mixtures: Appbutamone-DCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 Substrates
  9. Drug

    Nepidermin

    go.drugbank.com/drugs/DB14145
    Investigational

    Mixtures: EASYDEW DW EGF Derma Oneshot AmpouleInternational brands: Regen-D, Kang He Su
  10. Drug

    Fexofenadine

    go.drugbank.com/drugs/DB00950
    ApprovedInvestigational

    Fexofenadine is an over-the-counter second-generation antihistamine used in the treatment of various allergic symptoms. It is selective for the H1 receptor, carries little-to-no activity at off-targets, and does not cross the blood-brain...

    Mixtures: Allegra D-12 Hour, Allegra-DCategories: P-glycoprotein substrates