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Displaying results 5801 - 5810 of 10000 in total
  1. Drug

    Bimokalner

    go.drugbank.com/drugs/DB21717
    Investigational

    Bimokalner is under investigation in clinical trial NCT06521190 (ACOU085 for Hearing Loss Prevention in Testicular Cancer Patients Receiving Cisplatin). … Bimokalner is a small molecule drug. The usage of the INN stem '-kalner' in the name indicates that Bimokalner is a opener of calcium-activated (maxi-K) K+-channel.

  2. Drug

    Potassium triiodide

    go.drugbank.com/drugs/DB14492
    Investigational

    Categories: Compounds used in a research, industrial, or household setting
  3. Drug

    Nemonoxacin

    go.drugbank.com/drugs/DB06600
    Investigational

    Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use
  4. Drug

    Maridebart Cafraglutide

    go.drugbank.com/drugs/DB19339
    Investigational

    Maridebart Cafraglutide is under investigation in clinical trial NCT05669599 (Dose-ranging Study to Evaluate the Efficacy, Safety, and Tolerability of AMG 133 in Adult Subjects With Overweight or Obesity … , With or Without Type 2 Diabetes Mellitus).

  5. Drug

    VPM1002

    go.drugbank.com/drugs/DB15801
    Investigational

    VPM1002 is a recombinant BCG vaccine candidate expressing listeriolysin and deficient in urease that is generated in the genetic background of BCG Prague as it has a better safety profile than some other … This recombinant BCG, VPM1002, has been created in response and investigated for preventing pulmonary TB in newborns and TB recurrence in adults through post-exposure immunization.

  6. Drug

    Neladalkib

    go.drugbank.com/drugs/DB21712
    Investigational

    Neladalkib is under investigation in clinical trial NCT06765109 (Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC). … Neladalkib is a small molecule drug. The usage of the INN stem '-alkib' in the name indicates that Neladalkib is a ALK (anaplastic lymphoma kinase) inhibitor.

    Synonyms: an orally bioavailable ALK inhibitor (a macrocyclic compound containing nitrogen heterocycles)
  7. Drug

    AZD-8186

    go.drugbank.com/drugs/DB15029
    Investigational

    AZD-8186 is under investigation in clinical trial NCT03218826 (PI3Kbeta Inhibitor AZD8186 and Docetaxel in Treating Patients Advanced Solid Tumors With PTEN or PIK3CB Mutations That Are Metastatic or Cannot

  8. Drug

    SYNB1020

    go.drugbank.com/drugs/DB17667
    Investigational

    It was initially designed to convert ammonia to L-arginine [A258838] and granted orphan designation by the FDA for the treatment of urea cycle disorders in August 2016;[L45988] however, the manufacturer … discontinued further development of SYNB1020 to treat hyperammonemia due to a lack of evidence of ammonia-lowering activities by SYNB1020 in a Phase 1b/2a study.

  9. Drug

    Bacteroides thetaiotaomicron

    go.drugbank.com/drugs/DB17879
    Investigational

    Developed by 4D Pharma, Thetanix, an oral formulation comprising lyophilized Bacteroides thetaiotaomicron, is being investigated for the treatment of Crohn’s disease.[A259892] … Bacteroides thetaiotaomicron is a live biotherapeutic.

  10. Drug

    Carbetocin

    go.drugbank.com/drugs/DB01282
    ApprovedInvestigational

    Carbetocin is a drug used to control postpartum hemorrhage, bleeding after giving birth. … It is an analogue of oxytocin, and its action is similar to that of oxytocin -- it causes contraction of the uterus.

    Synonyms: 1-butanoic acid-2-(O-methyl-L-tyrosine)-1-carbaoxytocin, 1-butyric acid-2-(3-(p-methoxyphenyl)-L-alanine)oxytocinProducts: Carbetocin Aguettant 100 Mikrogramm/ml Injektionslösung in einer Fertigspritze, DURATOCIN RTS SOLUTION FOR INJECTION 100 MCG/ML