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Antipain
go.drugbank.com/drugs/DB15251Experimental[A214490] The binding of antipain to OPB has been used in molecular dynamic studies to identify other OPB inhibitors with more favourable pharmacodynamic and pharmacokinetic properties for potential development … [A214481] Early studies investigated the potential for antipain to alter DNA damage and chromosomal aberrations in irradiated cells or those treated with chemical mutagens such as _N_-methyl-_N_'-nitro
Covax-19™
go.drugbank.com/drugs/DB15846InvestigationalCovax-19™ was tested in animal studies, and shown to achieve potent antibody and T-cell responses against the COVID-19 spike protein. … As of June 2020, the vaccine is in Phase 1 trials to evaluate safety and immune responses (NCT04428073).
Epitestosterone
go.drugbank.com/drugs/DB07768ExperimentalThe ratio between testosterone/epitestosterone is used to monitor anabolic drug abuse. … Epitestosterone is the 17-alpha isomer of testosterone, derived from pregnenolone via the delta5-steroid pathway, and via 5-androstene-3-beta,17-alpha-diol.
RPI-78M
go.drugbank.com/drugs/DB05740ExperimentalRPI-78M is being developed for the treatment of multiple sclerosis (MS). … Other neurological disorders that may be served by RPI-78M include myasthenia gravis (MG), muscular dystrophy (MD) and amyotrophic lateral sclerosis (ALS).
CIGB 300
go.drugbank.com/drugs/DB16464Investigationaland adenocarcinoma of the cervix) … CIGB-300, is under investigation in clinical trials for its potential to treat various conditions, including NCT01639638 (recurrent and nonrecurrent condyloma) and NCT01639625 (squamous cell carcinoma
TD-0903
go.drugbank.com/drugs/DB16463InvestigationalTD-0903 was investigated in clinical trials for its potential to treat acute lung injury (ALI) associated with COVID-19, including NCT04350736, NCT05091723 (a pharmacokinetics study in healthy participants
Anti-SARS-CoV-2 REGN-COV2
go.drugbank.com/drugs/DB15691InvestigationalThese antibodies have been formulated to bind to multiple locations on the SARS-COV-2 spike protein, preventing viral escape. … Anti-SARS-COV-2 REGN-COV2 is a combination of novel antibodies designed by Regeneron for both the prevention and treatment of SARS-COV-2, the virus that causes COVID-19.
Cositecan
go.drugbank.com/drugs/DB05806InvestigationalCositecan is the novel camptothecin derivative which is also known as Karenitecin. It has been developed for superior oral bioavailability and increased lactone stability. It is used to treat cancer.
Jojoba oil
go.drugbank.com/drugs/DB14252ApprovedJojoba oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Scutellaria lateriflora
go.drugbank.com/drugs/DB14339ApprovedScutellaria lateriflora is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.