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Survodutide
go.drugbank.com/drugs/DB18989InvestigationalSurvodutide is under investigation in clinical trial NCT06077864 (A Study to Test the Effect of Survodutide (BI 456906) on Cardiovascular Safety in People With Overweight or Obesity (SYNCHRONIZE™ - CVOT
Tetomilast
go.drugbank.com/drugs/DB05298InvestigationalTetomilast has been used in trials studying the treatment of Crohn Disease, Colitis, Ulcerative, and Chronic Obstructive Pulmonary Disease.
Verubecestat
go.drugbank.com/drugs/DB12285InvestigationalIn the study, administration of Verubecestat at doses of 12, 40 and 60 mg resulted in a dose-dependent and sustained reduction in the levels of Ab40, a measure of BACE1 activity, in CSF from baseline of … In July 2013, Merck announced positive results for Phase Ib trials of Verubecestat.
Bifunctional epoxide hydrolase 2
go.drugbank.com/drugs/DB15139InvestigationalBifunctional epoxide hydrolase 2 is under investigation in clinical trial NCT00654966 (Evaluation of the Effects of Urotensin-II and Soluble Epoxide Hydrolase Inhibitors on Skin Microvessel Tone in Patients … With Heart Failure, and in Healthy Volunteers).
NS-3728
go.drugbank.com/drugs/DB05835ExperimentalNS3728 is an orally active chloride channel blocker for the treatment of cancer.
Synonyms: N-[4-bromo-2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]-N'-[3,5-bis(trifluoromethyl)phenyl]ureaABT-560
go.drugbank.com/drugs/DB06093ExperimentalABT-560 is a neuronal nicotinic receptor (NNR) modulator, which has shown promise in preclinical models relevant for the treatment of cognitive deficits.
Asundexian
go.drugbank.com/drugs/DB19088InvestigationalAsundexian is under investigation in clinical trial NCT05686070 (A Study to Test Asundexian for Preventing a Stroke Caused by a Clot in Participants After an Acute Ischemic Stroke or After a High-risk … Transient Ischemic Attack, a So-called Mini Stroke).
Synonyms: 1(2h)-pyridineacetamide, n-(4-(aminocarbonyl)-3-fluorophenyl)-4-(5-chloro-2-(4-(trifluoromethyl)-1h-1,2,3-triazol-1-yl)phenyl)-.alpha.-ethyl-5-methoxy-2-oxo-, (.alpha.s)-D-Asparagine
go.drugbank.com/drugs/DB03943ExperimentalA non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue. It is biosynthesized from ASPARTIC ACID and AMMONIA by asparagine synthetase. … (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed)
R-348
go.drugbank.com/drugs/DB06321InvestigationalSynonyms: 5-Fluoro-N-(4-methyl-3-propionylaminosulfonylphenyl)-N'-(4-(prop-2-ynyloxy)phenyl)-2,4-pyrimidinediamineAmylopectin
go.drugbank.com/drugs/DB14927ExperimentalAmylopectin is under investigation in clinical trial NCT01708694 (Role of Slowly Digesible Starch on Diabetes Risk Factors).