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Human C1-esterase inhibitor
go.drugbank.com/drugs/DB06404ApprovedInvestigational[L16586, L16606] This drug is indicated for prophylaxis and treatment of Hereditary Angioedema (HAE), a human genetic disorder caused by a shortage of C1 inhibitor activity that results in an overreaction
Products: CİNRYZE 500 IU/5 ML IV ENJEKSİYONLUK ÇÖZELTİ İÇİN LİYOFİLİZE TOZ VE ÇÖZÜCÜ, 2 ADETRecombinant Bacterial ACE2 Receptors-like Enzyme
go.drugbank.com/drugs/DB15741InvestigationalB38-CAP is structured as a carboxypeptidase and derived from _Paenibacillus sp._ The molecule, an Angiotensin Converting Enzyme 2 (ACE2)-like enzyme, shares structural similarities to the mammalian ACE2 … B38-CAP is an ACE2-like enzyme which decreases angiotensin II levels. It is being investigated for treating hypertension, myocardial fibrosis, and cardiac dysfunction.
AME-527
go.drugbank.com/drugs/DB05879ExperimentalAME-527 is a humanized monoclonal antibody that recognizes human TNF-alpha (hTNF-alpha) with high affinity and specificity. … AME-527 was generated by protein engineering and identified from a library of antibody variants based on its improved binding properties.
Dexchlorpheniramine
go.drugbank.com/drugs/DB13679InvestigationalThe salt form dexchlorpheniramine maleate as the active ingredient is available as a prescription drug indicated for adjunctive therapy for allergic and anaphylactic reactions. … Dexchlorpheniramine is a potent S-enantiomer of chlorpheniramine.
Plosaracetam
go.drugbank.com/drugs/DB21594InvestigationalPlosaracetam has a monoisotopic molecular weight of 330.05 Da. … Plosaracetam is a small molecule drug. The usage of the INN stem '-racetam' in the name indicates that Plosaracetam is a piracetam type amide type nootrope agent.
Icalcaprant
go.drugbank.com/drugs/DB21651InvestigationalIcalcaprant has a monoisotopic molecular weight of 406.2 Da. … Icalcaprant is a small molecule drug. The usage of the INN stem '-caprant' in the name indicates that Icalcaprant is a kappa-opioid receptor (KOR) antagonist.
Olomorasib
go.drugbank.com/drugs/DB21697InvestigationalOlomorasib has a monoisotopic molecular weight of 528.08 Da. … Olomorasib is a small molecule drug. The usage of the INN stem '-rasib' in the name indicates that Olomorasib is a Ras protein inhibitor.
Istisociclib
go.drugbank.com/drugs/DB21703InvestigationalIstisociclib has a monoisotopic molecular weight of 287.21 Da. … Istisociclib is a small molecule drug. The usage of the INN stem '-ciclib' in the name indicates that Istisociclib is a cyclin dependant kinase inhibitor.
Atirmociclib
go.drugbank.com/drugs/DB21733InvestigationalAtirmociclib has a monoisotopic molecular weight of 463.18 Da. … Atirmociclib is a small molecule drug. The usage of the INN stem '-ciclib' in the name indicates that Atirmociclib is a cyclin dependant kinase inhibitor.
Albinterferon Alfa-2B
go.drugbank.com/drugs/DB05396InvestigationalHuman Genome Sciences is developing Albuferon as a potential treatment for chronic hepatitis C. … The drug was under investigation as an alternative to pegylated IFN-α-2a for the treatment of hepatitis C.