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Displaying results 5861 - 5870 of 10000 in total
  1. Drug

    LetibotulinumtoxinA

    go.drugbank.com/drugs/DB16820
    Approved

    [L42330] It is a 900 kDa multimeric complex comprising a 150 kDa toxin, a 130 kDa non-toxic non-haemagglutinating protein, and various other haemagglutinins. … [A249920] LetibotulinumtoxinA is a type A botulinum neurotoxin produced from fermentation of _Clostridium botulinum_ strain CBFC26.

    Synonyms: BoNT/A-DSCategories: Botulinum Toxins, Type A
  2. Drug

    Antilymphocyte immunoglobulin (horse)

    go.drugbank.com/drugs/DB09312
    ApprovedInvestigational

    It is formed by inoculating a horse with an antigen (human thymoyctes) which then induces the horse immune system's B-lymphocytes to produce IgG immunoglobulins specific for that antigen. … The result is polyclonal IgG that is then purified from the horse's serum to produce a usable drug product that can be used for immunosuppression.

    Products: Atgam Sterile Solution IV 50mg/ml
  3. Drug

    V591

    go.drugbank.com/drugs/DB16438
    Investigational

    The V591 vaccine, part of Merck’s COVID-19 vaccine programming, was developed using a modified measles vaccine virus as a vector for COVID-19 antigen delivery[L30593].

  4. Drug

    N-(3-cyclopropyl-1H-pyrazol-5-yl)-2-(2-naphthyl)acetamide

    go.drugbank.com/drugs/DB06944
    Experimental

    These are compounds containing a naphthalene moiety, which consists of two fused benzene rings. … N-(3-cyclopropyl-1H-pyrazol-5-yl)-2-(2-naphthyl)acetamide is a solid. This compound belongs to the naphthalenes.

  5. Drug

    α-Methylacetylfentanyl

    go.drugbank.com/drugs/DB01532
    ExperimentalIllicit

    α-Methylacetylfentanyl is an analog of fentanyl with opioid analgesic properties.

  6. Drug

    R411

    go.drugbank.com/drugs/DB05468
    Experimental

    It is a dual-acting competitive integrin antagonist (as compared to previously developed single integrin antagonists or SIAs) that prevents binding of V-CAM1 to either a4b1 or a4b7. … R411 is a non-steroid oral medicine for the treatment of asthma. It is not immunosuppressive, but blocks the activation and recruitment of cells involved in respiratory inflammation.

  7. Drug

    5-Methoxy-N,N-diisopropyltryptamine

    go.drugbank.com/drugs/DB01441
    ExperimentalIllicit

    5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT) is a tryptamine derivative and shares many similarities with schedule I tryptamine hallucinogens such as alpha-ethyltryptamine, N,N-dimethyltryptamine, … Since 1999, there has been a growing popularity of 5-MeO-DIPT among drug abusers. This substance is abused for its hallucinogenic effects.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  8. Drug

    Guanosine tetraphosphate

    go.drugbank.com/drugs/DB04022
    Experimental

    This nucleotide serves as a messenger to turn off the synthesis of ribosomal RNA when amino acids are not available for protein synthesis. … Guanosine tetraphosphate is a guanine nucleotide containing four phosphate groups.

  9. Drug

    Tozasertib

    go.drugbank.com/drugs/DB19675
    Investigational

    Tozasertib is a small molecule drug. The usage of the INN stem '-sertib' in the name indicates that Tozasertib is a serine/threonine kinase inhibitor. … Tozasertib has a monoisotopic molecular weight of 464.21 Da.

  10. Drug

    BB-301

    go.drugbank.com/drugs/DB17011
    Investigational

    BB-301 is a modified AAV serotype 9 (AAV9) capsid expressing a unique, single bifunctional construct promoting co-expression of both codon-optimized Poly-A Binding Protein Nuclear-1 (PABPN1) and two small